Articles with "elvn 002" as a keyword



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Abstract 4019: Preclinical activity of ELVN-002: A potent, selective, and irreversible HER2 and pan-HER2 mutant small molecule inhibitor for the treatment of HER2 driven malignancies

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-4019

Abstract: Mutation or amplification of the human epidermal growth factor receptor 2 (HER2) gene has been identified in numerous solid tumor types, including non-small cell lung cancer (NSCLC), breast, and colorectal cancer. These genetic alterations are… read more here.

Keywords: her2 mutant; elvn 002; her2; activity ... See more keywords