Embryo-Based Large Fragment Knock-in in Mammals: Why, How and What’s Next
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DOI: 10.3390/genes11020140
Abstract: Endonuclease-mediated genome editing technologies, most notably CRISPR/Cas9, have revolutionized animal genetics by allowing for precise genome editing directly through embryo manipulations. As endonuclease-mediated model generation became commonplace, large fragment knock-in remained one of the most… read more here.
Keywords: knock; fragment knock; large fragment; embryo based ... See more keywords