Assisted oocyte activation does not overcome recurrent embryo developmental problems.
Sign Up to like & getrecommendations! Published in 2023 at "Human reproduction"
DOI: 10.1093/humrep/dead051
Abstract: STUDY QUESTION Can recurrent embryo developmental problems after ICSI be overcome by assisted oocyte activation (AOA)? SUMMARY ANSWER AOA did not improve blastocyst formation in our patient cohort with recurrent embryo developmental problems after ICSI.… read more here.
Keywords: fertilization; development; embryo developmental; aoa ... See more keywords
Decreased embryo developmental potential and lower cumulative pregnancy rate in men with multiple morphological abnormalities of the sperm flagella
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2024.1377780
Abstract: Objective Multiple morphological abnormalities of the sperm flagella (MMAF) is characterized by abnormal flagellar phenotypes, which is a particular kind of asthenoteratozoospermia. Previous studies have reported a comparable intracytoplasmic sperm injection (ICSI) outcome in terms… read more here.
Keywords: developmental potential; rate; pregnancy rate; multiple morphological ... See more keywords
Does Trophectoderm Mitochondrial DNA Content Affect Embryo Developmental and Implantation Potential?
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23115976
Abstract: A retrospective case control study was undertaken at the molecular biology department of a private center for reproductive medicine in order to determine whether any correlation exists between the mitochondrial DNA (mtDNA) content of trophectoderm… read more here.
Keywords: day; embryo developmental; mitochondrial dna; mtdna ... See more keywords
Zebrafish Embryo Developmental Toxicity Assay (ZEDTA) for Regulatory Testing—Protocol Optimization and Historical Control Data
Sign Up to like & getrecommendations! Published in 2025 at "Toxics"
DOI: 10.3390/toxics13100874
Abstract: The Zebrafish Embryo Developmental Toxicity Assay (ZEDTA) is a promising and innovative method with potential to replace the screening of teratogenic substances in mammals during preclinical development. However, a harmonized and validated protocol does not… read more here.
Keywords: zebrafish embryo; protocol; embryo developmental; developmental toxicity ... See more keywords