Deconvolving Passive and Active Targeting of Liposomes Bearing LDL Receptor Binding Peptides Using the Zebrafish Embryo Model.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202310781
Abstract: Improving target versus off-target ratio in nanomedicine remains a major challenge for increasing drug bioavailability and reducing toxicity. Active targeting using ligands on nanoparticle surfaces is a key approach but has limited clinical success. A… read more here.
Keywords: using zebrafish; receptor; zebrafish embryo; embryo model ... See more keywords
Autoradiography of Intracerebral Tumours in the Chick Embryo Model: A Feasibility Study Using Different PET Tracers
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-025-01983-9
Abstract: In addition to rodent models, the chick embryo model has gained attention for radiotracer evaluation. Previous studies have investigated tumours on the chorioallantoic membrane (CAM), but its value for radiotracer imaging of intracerebral tumours has… read more here.
Keywords: chick embryos; intracerebral tumours; chick embryo; embryo model ... See more keywords
Effects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience Reports"
DOI: 10.1042/bsr20180185
Abstract: Hypoxia episodes and areas in tumours have been associated with metastatic dissemination and poor prognosis. Given the link between tumour tissue oxygen levels and cellular metabolic activity, we hypothesised that the metabolic profile between metastatic… read more here.
Keywords: embryo model; effects hypoxic; hypoxic preconditioning; tumour oxygenation ... See more keywords
The zebrafish embryo model: unveiling its potential for investigating phage therapy against methicillin-resistant Staphylococcus aureus infection
Sign Up to like & getrecommendations! Published in 2024 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00561-24
Abstract: ABSTRACT Staphylococcus aureus is a pathogenic bacterium responsible for a broad spectrum of infections, including cutaneous, respiratory, osteoarticular, and systemic infections. It poses a significant clinical challenge due to its ability to develop antibiotic resistance.… read more here.
Keywords: aureus; zebrafish embryo; embryo model; infection ... See more keywords
A Zebrafish Embryo Model to Screen Potential Therapeutic Compounds in Sapindaceae Poisoning
Sign Up to like & getrecommendations! Published in 2024 at "Molecules"
DOI: 10.3390/molecules29204954
Abstract: Hypoglycin A (HGA) and methylenecyclopropylglycine (MCPrG) are protoxins produced by Sapindaceae plants, particularly Acer pseudoplatanus, and are responsible for causing atypical myopathy (AM) in equids. These protoxins metabolise into toxic compounds, such as methylenecyclopropylacetyl-CoA (MCPA-CoA),… read more here.
Keywords: compounds sapindaceae; zebrafish embryo; embryo model; therapeutic compounds ... See more keywords
Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model
Sign Up to like & getrecommendations! Published in 2019 at "Nanomaterials"
DOI: 10.3390/nano9010122
Abstract: The use of chitosan nanoparticles (ChNPs) in various biological and environmental applications is attracting great interest. However, potential side effects related to ChNP toxicity remain the major limitation hampering their wide application. For the first… read more here.
Keywords: embryo model; zebrafish embryo; chitosan nanoparticles; size ... See more keywords