Which embryo selection method should be offered to the patients?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-019-01443-8
Abstract: Despite the vast improvements of assisted reproduction, IVF live birth rates have only slowly improved. Delayed childbearing and the well-known negative effect of age on reproduction is one likely explanation. Another often cited explanation is… read more here.
Keywords: meta analyses; embryo selection; kinetic markers; selection ... See more keywords
Biomechanics and developmental potential of oocytes and embryos.
Sign Up to like & getrecommendations! Published in 2017 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2017.09.016
Abstract: The high incidence of multiple embryo transfers is evidence of the need for better methods of embryo selection. Additionally, methods to determine the reproductive competence of unfertilized oocytes are critically needed to inform the growing… read more here.
Keywords: embryo selection; biomechanical properties; developmental potential; biomechanics ... See more keywords
Status of preimplantation genetic testing and embryo selection.
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive biomedicine online"
DOI: 10.1016/j.rbmo.2018.08.001
Abstract: At the recent 2018 PGDIS congress, a review of randomized controlled trials of preimplantation genetic testing for aneuploidies (PGT-A) showed improved ongoing pregnancy rates per transfer in experienced centres and in women aged 35 years… read more here.
Keywords: genetic testing; embryo selection; status preimplantation; preimplantation genetic ... See more keywords
O-098 Embryo selection using Artificial Intelligence (AI): Epistemic and ethical considerations
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab125.034
Abstract: What are the epistemic and ethical considerations of clinically implementing Artificial Intelligence (AI) algorithms in embryo selection? AI embryo selection algorithms used to date are “black-box” models with significant epistemic and ethical issues, and there… read more here.
Keywords: epistemic ethical; embryo selection; selection; artificial intelligence ... See more keywords
Three models for the regulation of polygenic scores in reproduction
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Ethics"
DOI: 10.1136/medethics-2020-106588
Abstract: The past few years have brought significant breakthroughs in understanding human genetics. This knowledge has been used to develop ‘polygenic scores’ (or ‘polygenic risk scores’) which provide probabilistic information about the development of polygenic conditions… read more here.
Keywords: embryo selection; polygenic scores; genetics; disease ... See more keywords