Selective Translation of Maternal mRNA by eIF4E1B Controls Oocyte to Embryo Transition
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205500
Abstract: Maternal messenger ribonucleic acids (mRNAs) are driven by a highly orchestrated scheme of recruitment to polysomes and translational activation. However, selecting and regulating individual mRNAs for the translation from a competitive pool of mRNAs are… read more here.
Keywords: embryo transition; translation; mrna; selective translation ... See more keywords
Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1807918115
Abstract: Significance Reactive oxygen species (ROS) increase with age and have been shown to negatively impact age-related diseases. However, the physiological roles they might play in development have not been extensively characterized. Here, we show that… read more here.
Keywords: state; embryo transition; transition; oocyte embryo ... See more keywords
Translatome analysis at the egg-to-embryo transition in sea urchin
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky258
Abstract: Abstract Early embryogenesis relies on the translational regulation of maternally stored mRNAs. In sea urchin, fertilization triggers a dramatic rise in translation activity, necessary for the onset of cell division. Here, the full spectrum of… read more here.
Keywords: fertilization; embryo transition; egg embryo; sea urchin ... See more keywords
Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1009390
Abstract: Post-transcriptional regulation of gene expression is crucial during the oocyte-to-embryo transition, a highly dynamic process characterized by the absence of nuclear transcription. Thus, changes to the RNA content are solely dependent on RNA degradation. Although… read more here.
Keywords: embryo transition; ski7; rna; oocyte embryo ... See more keywords