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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/7651_2021_440
Abstract: Human embryonic stem cells (hESCs) can differentiate into any cell lineage (pluripotency potential) derived from the three germ layers: ectoderm, mesoderm, and endoderm. Pluripotency is usually demonstrated in vitro by spontaneous differentiation of hESCs grown…
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Keywords:
embryoid bodies;
embryonic stem;
differentiation;
stem ... See more keywords
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Published in 2019 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-019-04414-2
Abstract: We examined the efficacy of embryoid bodies from 6-day induced pluripotent stem cells an in vivo sepsis model. Injection of embryoid bodies to septic mice improved the condition of their lungs and significantly increased their…
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Keywords:
sphingosine phosphate;
pluripotent stem;
embryoid bodies;
induced pluripotent ... See more keywords
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Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108222
Abstract: SUMMARY Early developmental specification can be modeled by differentiating embryonic stem cells (ESCs) to embryoid bodies (EBs), a heterogeneous mixture of three germ layers. Here, we combine single-cell transcriptomics and genetic recording to characterize EB…
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Keywords:
single cell;
genetic recording;
embryoid bodies;
cell ... See more keywords
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Published in 2022 at "Systems Biology in Reproductive Medicine"
DOI: 10.1080/19396368.2021.2007554
Abstract: ABSTRACT Tissue engineering is gaining use to investigate the application of its techniques for infertility treatment. The use of pluripotent embryonic cells for in vitro production of viable spermatozoa in testicular scaffolds is a promising…
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Keywords:
cell;
microscopy;
testis;
rat testis ... See more keywords