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Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24448
Abstract: The subcortical maternal complex (SCMC), composed of several maternal‐effect genes, is vital for the development of oocytes and early embryos. Variants of SCMC‐encoding genes (NLRP2, NLRP5, TLE6, PADI6, and KHDC3L, but not OOEP and ZBED3)…
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Keywords:
arrest;
nlrp5 identified;
mutations ooep;
ooep nlrp5 ... See more keywords
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1
Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2018.12.084
Abstract: Early Embryonic Arrest (EEA) is one of the major causes of female infertility. Genetic factors including specific genes and miRNAs may play pivotal roles on EEA. However, it is not well defined what genes and…
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Keywords:
seq;
embryonic arrest;
gene;
early embryonic ... See more keywords
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Published in 2017 at "Physiological and Biochemical Zoology"
DOI: 10.1086/692630
Abstract: Turtle embryos enter a state of arrested development in the oviduct, allowing the mother greater flexibility in her reproductive schedule. Development recommences once eggs transition from the hypoxic oviduct to the normoxic nest. Significant mortality…
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Keywords:
oviposition;
embryonic arrest;
mortality;
turtle eggs ... See more keywords
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1
Published in 2021 at "EMBO molecular medicine"
DOI: 10.15252/emmm.202115323
Abstract: Early embryonic arrest and fragmentation (EEAF) is a common phenotype observed in in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles. The phenotype causes female infertility and recurrent failed IVF/ICSI attempts. However, the molecular…
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Keywords:
medicine;
embryonic arrest;
arrest fragmentation;
mos ... See more keywords
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2
Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.819667
Abstract: Early embryonic arrest denotes premature termination of development in preimplantation embryos, which is one of the major phenotypes of recurrent assisted reproduction failure. Padi6 is proven to be a member of the subcortical maternal complex…
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Keywords:
padi6;
novel homozygous;
homozygous padi6;
embryonic arrest ... See more keywords
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2
Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1137869
Abstract: The aim of this study was to explore the microecological distribution and differences in the uterus and vaginal microbiome in women with early embryonic arrest and those with normal pregnancy by high-throughput sequencing. We systematically…
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Keywords:
normal pregnancy;
association vaginal;
embryonic arrest;
vaginal uterine ... See more keywords