Single cell expression analysis of primate-specific retroviruses-derived HPAT lincRNAs in viable human blastocysts identifies embryonic cells co-expressing genetic markers of multiple lineages
Sign Up to like & getrecommendations! Published in 2018 at "Heliyon"
DOI: 10.1016/j.heliyon.2018.e00667
Abstract: Chromosome instability and aneuploidies occur very frequently in human embryos, impairing proper embryogenesis and leading to cell cycle arrest, loss of cell viability, and developmental failures in 50–80% of cleavage-stage embryos. This high frequency of… read more here.
Keywords: single cell; embryonic cells; cells expressing; expression ... See more keywords
Embryonic Cells Redistribute SUMO1 upon Forced SUMO1 Overexpression
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DOI: 10.1128/mbio.01856-19
Abstract: Embryonic stem (ES) cells exhibit unusual transcriptional, proteomic, and signal response profiles, reflecting their unusual needs for rapid differentiation and replication. The work reported here demonstrated that mouse embryonic cell lines did not tolerate the… read more here.
Keywords: conjugation; overexpression; sumo1; overexpression sumo1 ... See more keywords
The Developmental Origins of Cancer: A Review of the Genes Expressed in Embryonic Cells with Implications for Tumorigenesis
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DOI: 10.3390/genes14030604
Abstract: Tumorigenesis, which involves the uncontrolled proliferation and differentiation of cells, has been observed to imitate a variety of pathways vital to embryonic development, motivating cancer researchers to explore the genetic origins of these pathways. The… read more here.
Keywords: tumorigenesis; origins cancer; cancer review; embryonic cells ... See more keywords