Research advances on embryonic diapause in mammals.
Sign Up to like & getrecommendations! Published in 2018 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2018.09.009
Abstract: Embryonic diapause occurs in over 130 species of mammals. In embryonic diapause, there is a reversible cessation phase in embryo development and subsequent reactivation and continuation of development with no adverse effects. This allows animals… read more here.
Keywords: advances embryonic; research advances; diapause mammals; diapause ... See more keywords
Expression of calcineurin in relation to the embryonic diapause process in the silkworm, Bombyx mori.
Sign Up to like & getrecommendations! Published in 2019 at "Comparative biochemistry and physiology. Part A, Molecular & integrative physiology"
DOI: 10.1016/j.cbpa.2018.10.013
Abstract: Calcineurin (CN) is a Ca2+/calmodulin-activated serine/threonine protein phosphatase that is essential for translating Ca2+ signals into changes in cell function and development. In the present study, we investigated changes in CN expression during the process… read more here.
Keywords: developing eggs; diapause process; process; physiology ... See more keywords
Bombyxin/Akt signaling in relation to the embryonic diapause process of the silkworm, Bombyx mori.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of insect physiology"
DOI: 10.1016/j.jinsphys.2019.04.007
Abstract: Our previous study showed that phosphorylation of glycogen synthase kinase (GSK)-3β is related to the embryonic diapause process in Bombyx. However, the upstream signaling pathway was not clearly understood. In the present study, we examined… read more here.
Keywords: akt phosphorylation; diapause process; diapause; phosphorylation ... See more keywords
Expression of protein kinase C in relation to the embryonic diapause process in the silkworm, Bombyx mori.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of insect physiology"
DOI: 10.1016/j.jinsphys.2019.104010
Abstract: In the present study, we investigated the expression of protein kinase C (PKC) signaling during the embryonic diapause process of Bombyx mori. PKC activity, determined using an antibody to phosphorylated substrates of PKC, was found… read more here.
Keywords: diapause process; diapause eggs; diapause; pkc ... See more keywords
Targeted depletion of uterine glandular Foxa2 induces embryonic diapause in mice
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.03.15.484401
Abstract: Embryonic diapause is a reproductive strategy in which embryo development and growth is temporarily arrested within the uterus to ensure the survival of neonates and mothers during unfavorable conditions. Pregnancy is reinitiated when conditions become… read more here.
Keywords: embryonic diapause; foxa2; depletion uterine; mice ... See more keywords
Abstract GS1-07: Treatment persistence of residual breast tumors through an embryonic diapause-like cancer cell state with suppressed myc activity
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs20-gs1-07
Abstract: Systemic breast cancer treatments often fail to achieve complete and sustained responses due to drug-persistent residual tumor foci, the “seed” for eventual relapse. Recent clinical studies have revealed that the chemo-persistent tumor cells undergo extensive… read more here.
Keywords: treatment; embryonic diapause; cancer; breast cancer ... See more keywords