Glutamine synthetase gene knockout-human embryonic kidney 293E cells for stable production of monoclonal antibodies.
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.26552
Abstract: Previously, it was inferred that a high glutamine synthetase (GS) activity in human embryonic kidney (HEK) 293E cells results in elevated resistance to methionine sulfoximine (MSX) and consequently hampers GS-mediated gene amplification and selection by… read more here.
Keywords: glutamine synthetase; 293e cells; embryonic kidney; hek293e ... See more keywords
Cell‐surface contacts determine volume and mechanical properties of human embryonic kidney 293 T cells
Sign Up to like & getrecommendations! Published in 2022 at "Cytoskeleton"
DOI: 10.1002/cm.21735
Abstract: Alterations in the organization of the cytoskeleton precede the escape of adherent cells from the framework of cell–cell and cell‐matrix interactions into suspension. With cytoskeletal dynamics being linked to cell mechanical properties, many studies elucidated… read more here.
Keywords: cell; embryonic kidney; surface; volume ... See more keywords
In vitro renal toxicity evaluation of copper-based metal-organic framework HKUST-1 on human embryonic kidney cells.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.116528
Abstract: HKUST-1 is currently studied for a very diverse range of applications. Despite its exciting potential, significant concerns remain regarding the safety of HKUST-1. Therefore, human embryonic kidney 293 (HEK293) cells were used to verify the… read more here.
Keywords: embryonic kidney; renal toxicity; hek293 cells; hkust ... See more keywords
Graphene oxide regulates cox2 in human embryonic kidney 293T cells via epigenetic mechanisms: dynamic chromosomal interactions
Sign Up to like & getrecommendations! Published in 2018 at "Nanotoxicology"
DOI: 10.1080/17435390.2018.1425498
Abstract: Abstract To extend the applications of engineered nanomaterials, such as graphene oxide (GO), it is necessary to minimize cytotoxicity. However, the mechanisms underlying this cytotoxicity are unclear. Dynamic chromosomal interactions have been used to illustrate… read more here.
Keywords: graphene oxide; chromosomal interactions; embryonic kidney; dynamic chromosomal ... See more keywords
Mechanical properties of tunneling nanotube and its mechanical stability in human embryonic kidney cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.955676
Abstract: Tunneling nanotubes (TNTs) are thin membrane tubular structures that interconnect physically separated cells. Growing evidence indicates that TNTs play unique roles in various diseases by facilitating intercellular transfer of signaling and organelles, suggesting TNTs as… read more here.
Keywords: embryonic kidney; human embryonic; mechanical stability; mechanical properties ... See more keywords
Embryonic Kidney Development, Stem Cells and the Origin of Wilms Tumor
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.3390/genes12020318
Abstract: The adult mammalian kidney is a poorly regenerating organ that lacks the stem cells that could replenish functional homeostasis similarly to, e.g., skin or the hematopoietic system. Unlike a mature kidney, the embryonic kidney hosts… read more here.
Keywords: wilms tumor; stem cells; embryonic kidney; kidney ... See more keywords