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Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.10.009
Abstract: Summary Mammals encode ∼5,000 integral membrane proteins that need to be inserted in a defined topology at the endoplasmic reticulum (ER) membrane by mechanisms that are incompletely understood. Here, we found that efficient biogenesis of…
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Keywords:
insertion;
membrane protein;
topology;
emc ... See more keywords
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Published in 2019 at "Microelectronics Reliability"
DOI: 10.1016/j.microrel.2019.113458
Abstract: Abstract Silicon carbide (SiC) power devices suitable for high-frequency, high-power density and high-temperature applications, and thus gain a broad prospect in the electric vehicle (EV) charger area. However, the high-frequency switching of SiC devices under…
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Keywords:
power module;
charger;
power;
emc ... See more keywords
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Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/4559550
Abstract: Pulmonary epithelial-myoepithelial carcinoma (P-EMC) is an exceptionally rare subtype of salivary gland lung tumor originating from tracheobronchial glands. P-EMC is a biphasic tumor consisting of an inner layer of epithelial cells and an outer layer…
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Keywords:
emc;
diagnosis;
epithelial myoepithelial;
pulmonary epithelial ... See more keywords
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Published in 2020 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-020-08774-2
Abstract: Extraskeletal myxoid chondrosarcoma (EMC) is an ultra-rare sarcoma of uncertain differentiation. Despite its name, EMC does not show a cartilaginous differentiation and has nothing to do with other chondrosarcoma subtypes. Nevertheless, similarly to conventional chondrosarcoma,…
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Keywords:
chondrosarcoma;
sarcoma;
myxoid chondrosarcoma;
extraskeletal myxoid ... See more keywords
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Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11030342
Abstract: Antimicrobial multidrug resistance (MDR) is a global challenge, not only for public health, but also for sustainable agriculture. Antibiotics used in humans should be ruled out for use in veterinary or agricultural settings. Applying antimicrobial…
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Keywords:
xenorhabdus szentirmaii;
non ribosomal;
bacterium;
emc ... See more keywords
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Published in 2020 at "eLife"
DOI: 10.7554/elife.62611
Abstract: Membrane protein biogenesis in the endoplasmic reticulum (ER) is complex and failure-prone. The ER membrane protein complex (EMC), comprising eight conserved subunits, has emerged as a central player in this process. Yet, we have limited…
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Keywords:
protein;
structural mechanistic;
mechanistic basis;
emc ... See more keywords