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Published in 2017 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2017.1341485
Abstract: ABSTRACT Introduction: LDL-cholesterol (LDL-C) is one of the most well-established risk factors for CV disease. Indeed, therapies that decrease LDL-C are proven to effectively reduce the risk of atherosclerotic CV disease. Monoclonal antibodies (mAbs) that…
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Keywords:
reduction;
biologic therapies;
risk;
pcsk9 ... See more keywords
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Published in 2024 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2024.1377055
Abstract: Primary Sjögren’s Syndrome (pSS) is a complex autoimmune disorder characterized by exocrine gland dysfunction, leading to dry eyes and mouth. Despite growing interest in biologic therapies for pSS, FDA approval has proven challenging due to…
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Keywords:
syndrome unveiling;
pathology;
frontiers sjogren;
emerging biologic ... See more keywords
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Published in 2024 at "Rheumatology"
DOI: 10.5114/reum/193351
Abstract: on the other hand, binds to the IL-5R α subunit on eosinophils and basophils, inducing eosinophil depletion via antibody-dependent cell-mediated cytotoxicity (ADCC), leading to a more direct and rapid reduction in eosinophil levels. One clinical…
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Keywords:
eosinophilic granulomatosis;
biologic therapies;
therapies targeting;
emerging biologic ... See more keywords