The Evolving Biomarker Landscape for Treatment Selection in Metastatic Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Drugs"
DOI: 10.1007/s40265-019-01165-2
Abstract: The approval of targeted therapies for metastatic colorectal cancer (mCRC) has led to important improvements in patient outcomes. However, it is still necessary to increase individualisation of treatments based on tumour genetic profiles to optimise… read more here.
Keywords: metastatic colorectal; biomarker; treatment; colorectal cancer ... See more keywords
Emerging biomarkers and screening for cognitive frailty
Sign Up to like & getrecommendations! Published in 2017 at "Aging Clinical and Experimental Research"
DOI: 10.1007/s40520-017-0741-8
Abstract: Physical frailty and cognitive frailty are two important targets of secondary intervention in aging research to narrow the gap between life and health span. The objective of the present narrative review was to examine clinical… read more here.
Keywords: research; cognitive frailty; cognitive impairment; frailty ... See more keywords
Emerging biomarkers for cardiac arrhythmias.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2019.11.012
Abstract: Cardiac arrhythmias are associated with substantial morbidity and mortality. Recent advances in the pathophysiological understanding of cardiac arrhythmia indicate that inflammation, fibrosis, and even autoimmune mechanisms could facilitate the development of arrhythmias by interfering either… read more here.
Keywords: biochemistry; emerging biomarkers; biomarkers cardiac; cardiac arrhythmias ... See more keywords
Emerging biomarkers for cancer immunotherapy in melanoma.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2017.09.004
Abstract: The treatment and prognosis of metastatic melanoma has changed substantially since the advent of novel immune checkpoint inhibitors (ICI), agents that enhance the anti-tumor immune response. Despite the success of these agents, clinically actionable biomarkers… read more here.
Keywords: melanoma; biomarkers cancer; immunotherapy melanoma; cancer immunotherapy ... See more keywords
Advances in diabetic cardiomyopathy: current and potential management strategies and emerging biomarkers
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Medicine and Surgery"
DOI: 10.1097/ms9.0000000000002857
Abstract: Background: Diabetic cardiomyopathy (DCM) is a significant complication of diabetes mellitus (DM) and a major contributor to heart failure (HF). Despite its prevalence and impact, there is a notable lack of targeted therapies, highlighting the… read more here.
Keywords: strategies emerging; diabetic cardiomyopathy; cardiomyopathy current; advances diabetic ... See more keywords
The development for emerging biomarkers of lymphangioleiomyomatosis
Sign Up to like & getrecommendations! Published in 2024 at "Orphanet Journal of Rare Diseases"
DOI: 10.1186/s13023-024-03455-9
Abstract: Lymphangioleiomyomatosis (LAM) is a rare, slowly progressing, low-grade metastatic tumor primarily affecting women. Currently, vascular endothelial growth factor–D (VEGF-D) is the only validated diagnostic biomarker, enabling diagnosis of LAM without the need for lung biopsy… read more here.
Keywords: lam; lam lam; development emerging; biomarkers lymphangioleiomyomatosis ... See more keywords
Current and emerging biomarkers of frailty in the elderly
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Interventions in Aging"
DOI: 10.2147/cia.s168687
Abstract: The term “frailty” is used to describe a subset of older adults who appear weaker and more vulnerable than their age-matched counterparts, despite having similar comorbidities, demography, sex, and age. The diagnosis of frailty is… read more here.
Keywords: biomarkers frailty; emerging biomarkers; current emerging; frailty elderly ... See more keywords
Emerging Biomarkers for Early Detection and Prognosis of Liver Diseases.
Sign Up to like & getrecommendations! Published in 2025 at "Current pharmaceutical design"
DOI: 10.2174/0113816128384721250924030943
Abstract: INTRODUCTION The purpose of this research is to review and evaluate both traditional and emerging biomarkers used in the diagnosis, monitoring, and treatment of liver diseases. The study aims to highlight how these biomarkers-such as… read more here.
Keywords: micrornas exosomes; liver diseases; early detection; liver ... See more keywords
T3 and T4 autoantibodies: emerging biomarkers for evaluating thyroid disorders
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2025.1537222
Abstract: Introduction and objectives The clinical significance of thyroid hormone autoantibodies, specifically triiodothyronine autoantibodies (T3-Ab) and thyroxine autoantibodies (T4-Ab), is not well understood due to current detection method limitations. This study investigated the clinical utility of… read more here.
Keywords: detection; autoantibodies emerging; thyroid hormone; mclia kit ... See more keywords
Mitochondrial microRNAs (mitomiRs) as emerging biomarkers and therapeutic targets for chronic human diseases
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2025.1555563
Abstract: Mitochondria are membrane-bound cell organelles that undertake the majority of the energetic and metabolic processes within the cell. They are also responsible for mediating multiple apoptotic pathways, balancing redox charges, and scavenging reactive oxygen species.… read more here.
Keywords: therapeutic targets; mitomirs emerging; micrornas mitomirs; biomarkers therapeutic ... See more keywords
Emerging Biomarkers and Therapeutic Strategies for Refractory Bullous Pemphigoid
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.718073
Abstract: Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disorder in the elderly. Systemic and topical use of glucocorticoids and immunosuppressants has been shown to be effective in most patients. However, refractory BP patients… read more here.
Keywords: strategies refractory; therapeutic strategies; bullous pemphigoid; emerging biomarkers ... See more keywords