The Evolving Biomarker Landscape for Treatment Selection in Metastatic Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Drugs"
DOI: 10.1007/s40265-019-01165-2
Abstract: The approval of targeted therapies for metastatic colorectal cancer (mCRC) has led to important improvements in patient outcomes. However, it is still necessary to increase individualisation of treatments based on tumour genetic profiles to optimise… read more here.
Keywords: metastatic colorectal; biomarker; treatment; colorectal cancer ... See more keywords
Emerging biomarkers and screening for cognitive frailty
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DOI: 10.1007/s40520-017-0741-8
Abstract: Physical frailty and cognitive frailty are two important targets of secondary intervention in aging research to narrow the gap between life and health span. The objective of the present narrative review was to examine clinical… read more here.
Keywords: research; cognitive frailty; cognitive impairment; frailty ... See more keywords
Emerging biomarkers for cardiac arrhythmias.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2019.11.012
Abstract: Cardiac arrhythmias are associated with substantial morbidity and mortality. Recent advances in the pathophysiological understanding of cardiac arrhythmia indicate that inflammation, fibrosis, and even autoimmune mechanisms could facilitate the development of arrhythmias by interfering either… read more here.
Keywords: biochemistry; emerging biomarkers; biomarkers cardiac; cardiac arrhythmias ... See more keywords
Emerging biomarkers for cancer immunotherapy in melanoma.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2017.09.004
Abstract: The treatment and prognosis of metastatic melanoma has changed substantially since the advent of novel immune checkpoint inhibitors (ICI), agents that enhance the anti-tumor immune response. Despite the success of these agents, clinically actionable biomarkers… read more here.
Keywords: melanoma; biomarkers cancer; immunotherapy melanoma; cancer immunotherapy ... See more keywords
Current and emerging biomarkers of frailty in the elderly
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Interventions in Aging"
DOI: 10.2147/cia.s168687
Abstract: The term “frailty” is used to describe a subset of older adults who appear weaker and more vulnerable than their age-matched counterparts, despite having similar comorbidities, demography, sex, and age. The diagnosis of frailty is… read more here.
Keywords: biomarkers frailty; emerging biomarkers; current emerging; frailty elderly ... See more keywords
Emerging Biomarkers and Therapeutic Strategies for Refractory Bullous Pemphigoid
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.718073
Abstract: Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disorder in the elderly. Systemic and topical use of glucocorticoids and immunosuppressants has been shown to be effective in most patients. However, refractory BP patients… read more here.
Keywords: strategies refractory; therapeutic strategies; bullous pemphigoid; emerging biomarkers ... See more keywords
Current and Emerging Biomarkers Predicting Bone Metastasis Development
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.00789
Abstract: Bone is one of the preferential sites of distant metastases from malignant tumors, with the highest prevalence observed in breast and prostate cancers. Patients with bone metastases (BMs) may experience skeletal-related events, such as severe… read more here.
Keywords: current emerging; bone; predicting bone; emerging biomarkers ... See more keywords
Emerging Biomarkers for Immunotherapy in Glioblastoma
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DOI: 10.3390/cancers14081940
Abstract: Simple Summary Immunotherapy has shown clinical benefits in several solid cancers; still, glioblastoma remains very challenging to treat. Glioblastoma is the most frequent brain cancer and displays great heterogeneity. The standard of care has remained… read more here.
Keywords: emerging biomarkers; immunotherapy; cancer; biomarkers immunotherapy ... See more keywords
Present and Emerging Biomarkers in Immunotherapy for Metastatic Non-Small Cell Lung Cancer: A Review
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DOI: 10.3390/curroncol29020043
Abstract: Targeting the immune system, especially the PDL-1/PD-1 axis, has significantly improved the outcomes of metastatic lung cancer patients. However, only a portion of patients will benefit significantly from PD(L)1 therapeutics alone or in combination with… read more here.
Keywords: lung cancer; present emerging; lung; biomarkers immunotherapy ... See more keywords
Emerging Biomarkers for Predicting Clinical Outcomes in Patients with Heart Disease
Sign Up to like & getrecommendations! Published in 2023 at "Life"
DOI: 10.3390/life13010230
Abstract: Cardiovascular disease is most frequently caused by the development and progression of atherosclerosis. When coronary arteries are afflicted, and the stenoses caused by atherosclerotic plaques are severe enough, the metabolic supply-and-offer balance is disturbed, leading… read more here.
Keywords: clinical outcomes; predicting clinical; disease; heart ... See more keywords
Current and emerging biomarkers in metastatic colorectal cancer.
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DOI: 10.3747/co.26.5719
Abstract: Background The incorporation of novel biomarkers into therapy selection for patients with metastatic colorectal cancer (mcrc) has significantly improved outcomes. Optimal treatment planning now takes into account diverse characteristics of patients and their tumours to… read more here.
Keywords: metastatic colorectal; current emerging; colorectal cancer; ntrk fusions ... See more keywords