Emerging degrader technologies engaging lysosomal pathways
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Society Reviews"
DOI: 10.1039/d2cs00624c
Abstract: Targeted protein degradation (TPD) provides unprecedented opportunities for drug discovery. While the proteolysis-targeting chimera (PROTAC) technology has already entered clinical trials and changed the landscape of small-molecule drugs, new degrader technologies harnessing alternative degradation machineries,… read more here.
Keywords: emerging degrader; degrader technologies; technologies engaging; lysosomal pathways ... See more keywords