Potentiating SLC transporter activity: Emerging drug discovery opportunities
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2017.02.010
Abstract: Graphical abstract Figure. No caption available. Abstract Maintaining the integrity of cellular membranes is critical to protecting metabolic activities and genetic information from the environment. Regulation of transport across membranes of essential chemicals, including water,… read more here.
Keywords: slc transporters; emerging drug; potentiating slc; slc transporter ... See more keywords
Gastroparesis syndromes: emerging drug targets and potential therapeutic opportunities
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2023.2186222
Abstract: ABSTRACT Introduction Gastroparesis (Gp) and related disorders such as chronic unexplained nausea and vomiting and functional dyspepsia, known as gastropareis syndromes (GpS), have large unmet needs. Mainstays of GpS treatments are diet and drugs. Areas… read more here.
Keywords: drug targets; gastroparesis syndromes; targets potential; syndromes emerging ... See more keywords
Recently approved and emerging drug options for migraine prophylaxis
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2022.2102420
Abstract: ABSTRACT Introduction Migraine occupies the first position regarding the disability caused in female working population (15–49 years). Research in the field of prophylaxis in this pathology has made enormous strides in recent years. Areas covered… read more here.
Keywords: drug options; recently approved; migraine prophylaxis; approved emerging ... See more keywords
Current and emerging drug treatment strategies to tackle invasive community-associated methicillin-resistant Staphylococcus aureus (MRSA) infection: what are the challenges?
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2022.2161885
Abstract: ABSTRACT Introduction Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections represent a leading cause of purulent skin and soft tissue infections in some geographical regions. Traditionally, ‘old antibiotics’ such as trimethoprim-sulfamethoxazole, tetracyclines, clindamycin, chloramphenicol,vancomycin, and teicoplanin have… read more here.
Keywords: methicillin resistant; staphylococcus aureus; aureus mrsa; current emerging ... See more keywords
Emerging drug targets for colon cancer: A preclinical assessment
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2022.2039119
Abstract: ABSTRACT Introduction Colorectal cancer (CRC) is the second leading cause of cancer-related death in the United States. There have been improvements in screening, and therefore overall survival, but patients continue to present at late stages… read more here.
Keywords: drug targets; colon cancer; targets colon; emerging drug ... See more keywords
Osilodrostat - an emerging drug for the medical management of Cushing's disease.
Sign Up to like & getrecommendations! Published in 2022 at "Endokrynologia Polska"
DOI: 10.5603/ep.a2022.0009
Abstract: Cushing's disease (CD) is a rare endocrine disorder characterized by the overproduction of adrenocorticotropic hormone (ACTH) by pituitary adenoma followed by hypercortisolaemia with severe complications. Although transsphenoidal resection of the defined pituitary adenoma has been… read more here.
Keywords: disease osilodrostat; osilodrostat emerging; disease; management ... See more keywords