The emerging landscape of eukaryotic polyphosphatases.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14584
Abstract: Polyphosphate (polyP) is a conserved polymer of inorganic phosphate residues that can reach thousands of moieties in length. PolyP has been implicated in cellular functions ranging from energy and phosphate homeostasis to cell signalling in… read more here.
Keywords: phosphate; eukaryotic polyphosphatases; emerging landscape; landscape eukaryotic ... See more keywords
The emerging landscape of circular RNA in cardiovascular diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2018.08.012
Abstract: Circular RNAs (circRNAs), a large novel type of endogenous transcripts, have become a new research hotspot in the field of RNA biology. CircRNAs are mainly generated from exons or introns via multiple mechanisms, and the… read more here.
Keywords: landscape circular; circular rna; emerging landscape; rna ... See more keywords
The emerging landscape of in vitro and in vivo epigenetic allelic effects
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DOI: 10.12688/f1000research.11491.1
Abstract: Epigenetic mechanisms that cause maternally and paternally inherited alleles to be expressed differently in offspring have the potential to radically change our understanding of the mechanisms that shape disease susceptibility, phenotypic variation, cell fate, and… read more here.
Keywords: vivo epigenetic; vitro vivo; emerging landscape; allelic effects ... See more keywords
The Emerging Landscape of LINC01123 in Cancer: Roles, Mechanisms, and Clinical Significance.
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DOI: 10.2174/0113894501398484250903074131
Abstract: INTRODUCTION Long intergenic non-coding RNA 01123 (LINC01123) is a lncRNA located on the human chromosome 2q13. It is upregulated in various cancers and has been identified as an oncogene. Its expression is associated with the… read more here.
Keywords: cancer; clinical significance; linc01123; mechanisms clinical ... See more keywords
The Emerging Landscape of Natural Small-molecule Therapeutics for Huntington's Disease.
Sign Up to like & getrecommendations! Published in 2023 at "Current neuropharmacology"
DOI: 10.2174/1570159x21666230216104621
Abstract: Huntington's disease (HD) is a rare and fatal neurodegenerative disorder with no disease modifying therapeutics. HD is characterized by extensive neuronal loss and is caused by the inherited expansion of the huntingtin (HTT) gene that… read more here.
Keywords: small molecule; huntington disease; disease; natural products ... See more keywords