Purinergic receptors modulators: An emerging pharmacological tool for disease management
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DOI: 10.1002/med.21888
Abstract: Purinergic signaling is mediated through extracellular nucleotides (adenosine 5′‐triphosphate, uridine‐5'‐triphosphate, adenosine diphosphate, uridine‐5'‐diphosphate, and adenosine) that serve as signaling molecules. In the early 1990s, purines and pyrimidine receptors were cloned and characterized drawing the attention… read more here.
Keywords: pharmacological tool; purinergic receptors; emerging pharmacological; modulators emerging ... See more keywords
Emerging pharmacological therapies for ARDS: COVID-19 and beyond
Sign Up to like & getrecommendations! Published in 2020 at "Intensive Care Medicine"
DOI: 10.1007/s00134-020-06141-z
Abstract: ARDS, first described in 1967, is the commonest form of acute severe hypoxemic respiratory failure. Despite considerable advances in our knowledge regarding the pathophysiology of ARDS, insights into the biologic mechanisms of lung injury and… read more here.
Keywords: medicine; pharmacological therapies; ards covid; therapies ards ... See more keywords
Emerging pharmacological approaches to promote neurogenesis from endogenous glial cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2017.06.129
Abstract: Neurodegenerative disorders are emerging as leading contributors to the global disease burden. While some drug-based approaches have been designed to limit or prevent neuronal loss following acute damage or chronic neurodegeneration, regeneration of functional neurons… read more here.
Keywords: neurogenesis endogenous; pharmacological approaches; approaches promote; glial cells ... See more keywords
Keeping up with the therapeutic advances in schizophrenia: a review of novel and emerging pharmacological entities
Sign Up to like & getrecommendations! Published in 2019 at "CNS Spectrums"
DOI: 10.1017/s109285291900124x
Abstract: Schizophrenia remains one of the most severe medical diseases. Current dopamine modulating first-generation and second-generation antipsychotics target mainly positive symptoms, but not/inadequately negative and cognitive symptoms. Additional challenges include non-adherence and adverse effects, especially cardiometabolic… read more here.
Keywords: positive symptoms; review; keeping therapeutic; emerging pharmacological ... See more keywords
New approved and emerging pharmacological approaches to alcohol use disorder: a review of clinical studies
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2021.1892641
Abstract: ABSTRACT Abstract introduction: The number of medications approved for AUD is small and they generally have limited efficacy. We need new pharmacotherapies for the management of AUD. Areas covered: In this review, the authors aim… read more here.
Keywords: pharmacological approaches; approaches alcohol; approved emerging; new approved ... See more keywords
Emerging Pharmacological Treatments for Migraine in the Pediatric Population
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12040536
Abstract: Headaches in children and adolescents have high incidence and prevalence rates, with consequent elevated disability costs to individuals and the community. Pediatric migraine is a disorder with substantial clinical differences compared to the adult form.… read more here.
Keywords: treatments migraine; emerging pharmacological; pharmacological treatments; migraine pediatric ... See more keywords