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Published in 2022 at "Clinical Cardiology"
DOI: 10.1002/clc.23924
Abstract: The ability to opacify the left ventricle and delineate the endocardium after intravenous injection of microbubble ultrasound enhancing agents is of established value to quantify volumes and function in suboptimal unenhanced images, particularly in stress…
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Keywords:
established emerging;
contrast;
contrast agents;
enhancing agents ... See more keywords
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Published in 2021 at "Developmental Dynamics"
DOI: 10.1002/dvdy.398
Abstract: Membrane‐type matrix metalloproteinases (MT‐MMPs) are cell membrane‐tethered proteinases that belong to the family of the MMPs. Apart from their roles in degradation of the extracellular milieu, MT‐MMPs are able to activate through proteolytic processing at…
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Keywords:
emerging roles;
embryonic development;
cell;
roles mmps ... See more keywords
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Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202249866
Abstract: The intestinal tract harbors diverse microorganisms, host- and microbiota-derived metabolites, and potentially harmful dietary antigens. The epithelial barrier separates the mucosa, where diverse immune cells exist, from the lumen to avoid excessive immune reactions against…
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Keywords:
inflammatory bowel;
microbial bioactive;
host microbial;
emerging roles ... See more keywords
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Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1678
Abstract: Syndecan 2 (SDC2) belongs to a four‐member family of evolutionary conserved small type I transmembrane proteoglycans consisting of a protein core to which glycosaminoglycan chains are covalently attached. SDC2 is a cell surface heparan sulfate…
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Keywords:
sdc2;
emerging roles;
cancer progression;
roles syndecan ... See more keywords
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Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2116
Abstract: Breast cancer (BC), as a heterogeneous disease, is considered as one of the most common malignancies in women worldwide. The resistance of BC cells to therapeutic agents has remained a big challenge in the treatment…
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Keywords:
drug resistance;
exosomal mirnas;
emerging roles;
breast cancer ... See more keywords
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Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3595
Abstract: Environmental chemicals (ECs) are drawing great attention to their effects on health and their toxicological mechanisms are being investigated. Long non‐coding RNA (lncRNA) is a class of RNA with more than 200 nucleotides and does…
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Keywords:
emerging roles;
long non;
non coding;
expression ... See more keywords
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Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28401
Abstract: The mammalian target of rapamycin (mTOR) is a large Ser/Thr protein kinase that belongs to the phosphoinositide 3‐kinase (PI3K) family and mediates various physiological and pathological processes, especially cell proliferation, protein synthesis, autophagy, and cancer…
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Keywords:
emerging roles;
mtor signaling;
regulating mtor;
micrornas regulating ... See more keywords
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Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27547
Abstract: Multiple myeloma (MM) is a hematologic malignancy characterized by unrestricted secretion of monoclonal immunoglobulin and uncontrolled plasma cell proliferation. Extra‐medullary infiltration and drug resistance are two major obstacles in the treatment of MM. To solve…
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Keywords:
roles noncoding;
emerging roles;
multiple myeloma;
noncoding rnas ... See more keywords
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Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.mr0218-056rr
Abstract: Macrophages represent a heterogeneous group of cells, capable of carrying out distinct functions in a variety of organs and tissues. Even within individual tissues, their functions can vary with location. Tumor‐associated macrophages (TAMs) specialize into…
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Keywords:
chemotherapy;
metastasis;
cancer;
roles macrophages ... See more keywords
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Published in 2020 at "PROTEOMICS"
DOI: 10.1002/pmic.201900100
Abstract: Ubiquitination is a posttranslational modification characterized by the covalent attachment of ubiquitin molecules to protein substrates. The ubiquitination modification process is reversible, dynamic, and involved in the regulation of various biological processes, such as autophagy,…
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Keywords:
roles research;
research;
emerging roles;
tools atypical ... See more keywords
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Published in 2017 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1386
Abstract: Circular RNAs (circRNAs) represent a large class of noncoding RNAs (ncRNAs) that have recently emerged as regulators of gene expression. They have been shown to suppress microRNAs, thereby increasing the translation and stability of the…
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Keywords:
roles context;
circular rnas;
emerging roles;
context circular ... See more keywords