Emerging Targeted Therapy for Specific Genomic Abnormalities in Acute Myeloid Leukemia
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DOI: 10.3390/ijms23042362
Abstract: We describe recent updates of existing molecular-targeting agents and emerging novel gene-specific strategies. FLT3 and IDH inhibitors are being tested in combination with conventional chemotherapy for both medically fit patients and patients who are ineligible… read more here.
Keywords: emerging targeted; therapy; genomic abnormalities; targeted therapy ... See more keywords
New and Emerging Targeted Therapies for Hidradenitis Suppurativa
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DOI: 10.3390/ijms23073753
Abstract: Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease deriving from the hair follicles. The formation of inflammatory nodules, abscesses, fistulas, and sinus tracts is characterized by a large inflow of key pro-inflammatory mediators,… read more here.
Keywords: inflammatory; targeted therapies; new emerging; therapies hidradenitis ... See more keywords
Emerging Targeted Therapeutic Strategies to Overcome Imatinib Resistance of Gastrointestinal Stromal Tumors
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DOI: 10.3390/ijms24076026
Abstract: Gastrointestinal stromal tumors (GISTs) are the most common malignant mesenchymal neoplasms of the gastrointestinal tract. The gold standard for the diagnosis of GISTs is morphologic analysis with an immunohistochemical evaluation plus genomic profiling to assess… read more here.
Keywords: therapeutic strategies; gastrointestinal stromal; stromal tumors; emerging targeted ... See more keywords