Emerging treatments for neuromyelitis optica spectrum disorder
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neurology"
DOI: 10.1007/s00415-020-10083-3
Abstract: Neuromyelitis optica spectrum disorder (NMO-SD) has a worldwide prevalence of 0.5–10 persons per 100,000 population. It is characterised by inflammatory events centred on the optic nerve and spinal cord, often with poor recovery and subsequent… read more here.
Keywords: spectrum disorder; neuromyelitis optica; treatments neuromyelitis; optica spectrum ... See more keywords
Emerging Treatments for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis.
Sign Up to like & getrecommendations! Published in 2018 at "Clinics in liver disease"
DOI: 10.1016/j.cld.2017.08.013
Abstract: This review discusses completed phase II randomized clinical trials with high-quality published results for compounds that demonstrate effects on nonalcoholic steatohepatitis histology (obeticholic acid, elafibranor, and liraglutide). The authors also review the available preliminary data… read more here.
Keywords: emerging treatments; liver disease; treatments nonalcoholic; nonalcoholic steatohepatitis ... See more keywords
Part 2. Current and emerging treatments for hidradenitis suppurativa.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2019.08.089
Abstract: Treatment of hidradenitis suppurativa (HS) has remained challenging due to the many knowledge gaps regarding etiology. However, recent studies into the pathogenesis of HS have enabled the investigation of newer therapies. The second article in… read more here.
Keywords: treatments hidradenitis; current emerging; hidradenitis suppurativa; emerging treatments ... See more keywords
Emerging treatments for chronic urticaria
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2022.2042513
Abstract: ABSTRACT Introduction Across the globe, chronic urticaria (CU), i.e. chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CINDU), is common, long-persisting and difficult to manage. Still, at least one-fifth is not sufficiently controlled by guideline-recommended… read more here.
Keywords: treatments chronic; anti; chronic urticaria; anti ige ... See more keywords
Conventional and emerging treatments and controversies in myasthenia gravis
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2023.2207739
Abstract: ABSTRACT Introduction Myasthenia gravis (MG) is caused by IgG antibodies against different proteins at the neuromuscular junction. Anti-acetylcholine receptor (AChR) Abs are detected in the great majority of patients. MG management consists of long-term immunotherapy,… read more here.
Keywords: long term; emerging treatments; term; conventional emerging ... See more keywords
Approved and emerging treatments of malignant pleural mesothelioma in elderly patients
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Respiratory Medicine"
DOI: 10.1080/17476348.2019.1678386
Abstract: ABSTRACT Introduction: Malignant pleural mesothelioma (MPM) is a rare neoplasm with asbestos exposure as the dominant etiologic agent. Owing to the long latent period following exposure, MPM is often diagnosed late in life. Despite this,… read more here.
Keywords: treatments malignant; pleural mesothelioma; malignant pleural; approved emerging ... See more keywords
The role of the alternative pathway in paroxysmal nocturnal hemoglobinuria and emerging treatments
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2022.2109462
Abstract: ABSTRACT Introduction Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by uncontrolled activation of the terminal complement pathway, leading to intravascular hemolysis (IVH) and a prothrombotic state. Treatment with terminal complement (C5) inhibitors, the current standard of… read more here.
Keywords: complement; alternative pathway; nocturnal hemoglobinuria; emerging treatments ... See more keywords
Current and emerging treatments for acute promyelocytic leukemia
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Orphan Drugs"
DOI: 10.1080/21678707.2019.1684261
Abstract: ABSTRACT Introduction: The introduction of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) to clinical practice revolutionized the APL therapy and allowed development of chemotherapy-free regimen with high success rates in low- and intermediate-risk patients.… read more here.
Keywords: acute promyelocytic; current emerging; emerging treatments; treatments acute ... See more keywords
Established and Emerging Treatments for Patients with Inborn Errors of Metabolism.
Sign Up to like & getrecommendations! Published in 2020 at "NeoReviews"
DOI: 10.1542/neo.21-10-e699
Abstract: Inborn errors of metabolism (IEMs) are inherited defects in a metabolic pathway resulting in clinical disease. The overall goal of therapy is to restore metabolic homeostasis while minimizing the deleterious effects of the interruption. Conventional… read more here.
Keywords: established emerging; errors metabolism; treatments patients; emerging treatments ... See more keywords
Emerging treatments for COVID-19: déjà vu all over again?
Sign Up to like & getrecommendations! Published in 2020 at "Biomarkers in medicine"
DOI: 10.2217/bmm-2020-0524
Abstract: Promising therapeutic interventions were initially focused on three main components: plasma tissue factor (TF), thrombin and protein C The immune system and coagulation pathways interact through a complex array of cross-signaling, which could potentially result… read more here.
Keywords: emerging treatments; treatments covid;
Emerging Treatments for Disorders of Consciousness in Paediatric Age
Sign Up to like & getrecommendations! Published in 2022 at "Brain Sciences"
DOI: 10.3390/brainsci12020198
Abstract: The number of paediatric patients living with a prolonged Disorder of Consciousness (DoC) is growing in high-income countries, thanks to substantial improvement in intensive care. Life expectancy is extending due to the clinical and nursing… read more here.
Keywords: intensive care; age; paediatric age; emerging treatments ... See more keywords