Circular RNA vaccines against SARS-CoV-2 and emerging variants
Sign Up to like & getrecommendations! Published in 2022 at "Cell"
DOI: 10.1016/j.cell.2022.03.044
Abstract: As the emerging variants of SARS-CoV-2 continue to drive the worldwide pandemic, there is a constant demand for vaccines that offer more effective and broad-spectrum protection. Here, we report a circular RNA (circRNA) vaccine that… read more here.
Keywords: emerging variants; circular rna; sars cov; neutralizing antibodies ... See more keywords
Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-022-29288-3
Abstract: COVID-19 pathogen SARS-CoV-2 has infected hundreds of millions and caused over 5 million deaths to date. Although multiple vaccines are available, breakthrough infections occur especially by emerging variants. Effective therapeutic options such as monoclonal antibodies… read more here.
Keywords: sars cov; potency; antibody; emerging variants ... See more keywords
Nonsystematic Reporting Biases of the SARS-CoV-2 Variant Mu Could Impact Our Understanding of the Epidemiological Dynamics of Emerging Variants
Sign Up to like & getrecommendations! Published in 2023 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evad052
Abstract: Abstract Developing a timely and effective response to emerging SARS-CoV-2 variants of concern (VOCs) is of paramount public health importance. Global health surveillance does not rely on genomic data alone to identify concerning variants when… read more here.
Keywords: epidemiological dynamics; dynamics emerging; emerging variants; genomic data ... See more keywords
Mutations in emerging variants
Sign Up to like & getrecommendations! Published in 2021 at "Science"
DOI: 10.1126/science.371.6536.1328-i
Abstract: Coronavirus The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein mediates host cell entry and contains key epitopes for antibody binding. Emerging SARS-CoV-2 variants, which seem to have originated in immunocompromised patients with prolonged… read more here.
Keywords: emerging variants; science; variants mutations; mutations emerging ... See more keywords
Building a Resilient Scientific Network for COVID-19 and Beyond
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DOI: 10.1128/mbio.02223-22
Abstract: The continued evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates that the global scientific community monitor, assess, and respond to the evolving coronavirus disease (COVID-19) pandemic. But the current reactive approach to emerging… read more here.
Keywords: scientific community; building resilient; scientific network; resilient scientific ... See more keywords
A Detailed Overview of Immune Escape, Antibody Escape, Partial Vaccine Escape of SARS-CoV-2 and Their Emerging Variants With Escape Mutations
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.801522
Abstract: The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant variants of SARS-CoV-2 are emerging in due course of time with substantial mutations, having the immune escape property. Simultaneously, the vaccination drive against… read more here.
Keywords: vaccine escape; immune escape; emerging variants; escape ... See more keywords
Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.995412
Abstract: Anti-COVID antibody therapeutics have been developed but not widely used due to their high cost and escape of neutralization from the emerging variants. Here, we describe the development of VHH-IgA1.1, a nanobody IgA fusion molecule… read more here.
Keywords: vhh iga1; prophylactic therapeutic; emerging variants; inhalable affordable ... See more keywords
Transmission Dynamics and Genomic Epidemiology of Emerging Variants of SARS-CoV-2 in Bangladesh
Sign Up to like & getrecommendations! Published in 2022 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed7080197
Abstract: With the progression of the global SARS-CoV-2 pandemic, the new variants have become more infectious and continue spreading at a higher rate than pre-existing ones. Thus, we conducted a study to explore the epidemiology of… read more here.
Keywords: december 2020; emerging variants; epidemiology emerging; variants sars ... See more keywords
Epitope Identification and Designing a Potent Multi-epitope Vaccine Construct against SARS-CoV-2 Including the Emerging Variants
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Global Infectious Diseases"
DOI: 10.4103/jgid.jgid_96_21
Abstract: Introduction: The emergence of a novel coronavirus in China has turned into a SARS-CoV-2 pandemic with high fatality. As vaccines are developed through various strategies, their immunogenic potential may drastically vary and thus pose several… read more here.
Keywords: epitope vaccine; multi epitope; emerging variants; including emerging ... See more keywords