EMMPRIN expression is associated with metastatic progression in osteosarcoma
Sign Up to like & getrecommendations! Published in 2021 at "BMC Cancer"
DOI: 10.1186/s12885-021-08774-9
Abstract: Background Extracellular matrix metalloproteinase inducer (EMMPRIN), a cell-surface glycoprotein, is overexpressed in several cancer types. EMMPRIN induces a metastatic phenotype by triggering the production of matrix metalloproteinase proteins (MMPs) such as MMP1 and MMP2, and… read more here.
Keywords: emmprin; production; metastasis; expression ... See more keywords
The clinicopathological significance and prognostic value of EMMPRIN overexpression in cancers: evidence from 39 cohort studies
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DOI: 10.18632/oncotarget.19740
Abstract: Extracellular matrix metalloproteinase inducer (EMMPRIN) has been reported to be associated with tumor formation and invasion in many studies. However, the clinicopathological significance and prognosis of EMMPRIN in cancer patients remains inconclusive. Therefore, we conducted… read more here.
Keywords: clinicopathological significance; emmprin overexpression; significantly associated; emmprin ... See more keywords
Extracellular matrix metalloproteinase inducer in brain ischemia and intracerebral hemorrhage
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DOI: 10.3389/fimmu.2022.986469
Abstract: Increasing evidence from preclinical and clinical studies link neuroinflammation to secondary brain injury after stroke, which includes brain ischemia and intracerebral hemorrhage (ICH). Extracellular matrix metalloproteinase inducer (EMMPRIN), a cell surface transmembrane protein, is a… read more here.
Keywords: matrix; brain ischemia; emmprin; ischemia intracerebral ... See more keywords
Extracellular Vesicles Potentiate Medulloblastoma Metastasis in an EMMPRIN and MMP-2 Dependent Manner
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DOI: 10.3390/cancers15092601
Abstract: Simple Summary Medulloblastoma is the most prevalent malignant paediatric brain tumour, where metastasis and recurrence account for 95% of medulloblastoma-associated deaths. Secretion of extracellular vesicles (EVs) has emerged as a pivotal mediator for communication in… read more here.
Keywords: metastasis; matrix; extracellular vesicles; emmprin ... See more keywords