Empagliflozin inhibits increased Na influx in atrial cardiomyocytes of patients with HFpEF
Sign Up to like & getrecommendations! Published in 2024 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvae095
Abstract: Abstract Aims Heart failure with preserved ejection fraction (HFpEF) causes substantial morbidity and mortality. Importantly, atrial remodelling and atrial fibrillation are frequently observed in HFpEF. Sodium–glucose cotransporter 2 inhibitors (SGLT2i) have recently been shown to… read more here.
Keywords: atrial cardiomyocytes; increased influx; empagliflozin inhibits; cardiomyocytes patients ... See more keywords
Empagliflozin Inhibits IL-1β-Mediated Inflammatory Response in Human Proximal Tubular Cells
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DOI: 10.3390/ijms22105089
Abstract: SGLT2 inhibitor-related nephroprotection is—at least partially—mediated by anti-inflammatory drug effects, as previously demonstrated in diabetic animal and human studies, as well as hyperglycemic cell culture models. We recently presented first evidence for anti-inflammatory potential of… read more here.
Keywords: human proximal; response; empagliflozin inhibits; tubular cells ... See more keywords