Assessment of the methods used to detect HER2-positive advanced extramammary Paget’s disease
Sign Up to like & getrecommendations! Published in 2018 at "Medical Oncology"
DOI: 10.1007/s12032-018-1154-z
Abstract: The human epidermal growth factor receptor 2 (HER2) is recognized as an oncogene as well as a therapeutic target in various cancers. Certain patients with advanced extramammary Paget’s disease (EMPD) have also been reported to… read more here.
Keywords: her2 positive; empd; extramammary paget; advanced extramammary ... See more keywords
Efficacy of trastuzumab in HER-2-positive advanced extramammary Paget’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2022.2066472
Abstract: With strong interest, we read the review article, ‘Trastuzumab deruxtecan in HER-2-positive metastatic breast cancer and beyond’ by Perez et al. The authors summarize the characteristics and recent data regarding the efficacy and safety of… read more here.
Keywords: extramammary paget; empd; disease; therapy ... See more keywords
TRPS1 expression is sensitive and specific for primary extramammary Paget disease.
Sign Up to like & getrecommendations! Published in 2023 at "Histopathology"
DOI: 10.1111/his.14908
Abstract: AIMS Extramammary Paget disease (EMPD) is an epithelial neoplasm that can occur at many sites, including the vulva and scrotum. EMPD is characterised by the presence of neoplastic cells, in single cells and clusters, that… read more here.
Keywords: extramammary paget; vulva; empd; sensitive specific ... See more keywords
Survival analysis of patients with invasive extramammary Paget disease: implications of anatomic sites
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DOI: 10.1186/s12885-018-4257-1
Abstract: BackgroundExtramammary Paget disease (EMPD) is a rare malignant dermatosis with poorly defined outcomes. We investigated clinical characteristics of invasive EMPD at different anatomic sites and by subject demographics to determine prognostic factors for overall survival… read more here.
Keywords: anatomic sites; mortality; patients invasive; empd ... See more keywords
Extra-mammary Paget’s disease (EMPD) of the skin: A comprehensive genomic profiling (CGP) study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.9591
Abstract: 9591 Background: EMPD is an intraepidermal adenocarcinoma which frequently progresses into invasive/metastatic disease. Methods: 29 EMPD underwent hybrid-capture based CGP to evaluate all classes of genomic alterations (GA). Tumor mutational burden (TMB) was determined on… read more here.
Keywords: empd; disease; mammary paget; paget disease ... See more keywords
Usefulness of Mapping Biopsy in the Treatment of Penoscrotal Extramammary Paget’s Disease
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DOI: 10.1245/s10434-017-5947-7
Abstract: BackgroundExtramammary Paget’s disease (EMPD) is a rare cutaneous malignancy; however, the standard treatment of EMPD has not been established. In this study, we applied mapping biopsy to penoscrotal EMPD and evaluated its effects.MethodsA retrospective chart… read more here.
Keywords: biopsy; mapping biopsy; empd; local recurrence ... See more keywords
Extramammary Paget’s Disease: Diagnosis, Pathogenesis, and Treatment with Focus on Recent Developments
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DOI: 10.3390/curroncol28040260
Abstract: Extramammary Paget’s disease (EMPD) is a rare neoplasm that usually develops in apocrine gland-bearing areas, such as the vulva, scrotum, and penis. EMPD may present with a focal, multifocal, or an ectopic lesion. Clinically, EMPD… read more here.
Keywords: treatment; pathogenesis; extramammary paget; empd ... See more keywords