Hungry megakaryocytes on the hunt? An unusual case of extensive megakaryocyte emperipolesis
Sign Up to like & getrecommendations! Published in 2020 at "Hematology, Transfusion and Cell Therapy"
DOI: 10.1016/j.htct.2020.12.001
Abstract: An 11-year-old female presented with fever and thrombocytopenia (Platelet count 25 × 109/L). Bone marrow smears revealed hyperplasia and emperipolesis in all megakaryocytes containing intact lymphocytes and neutrophils. (Figs. 1 and 2) No etiology was… read more here.
Keywords: emperipolesis; hungry megakaryocytes; hunt unusual; unusual case ... See more keywords
Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.44031
Abstract: Bone marrow megakaryocytes engulf neutrophils in a phenomenon termed emperipolesis. We show here that emperipolesis is a dynamic process mediated actively by both lineages, in part through the β2-integrin/ICAM-1/ezrin pathway. Tethered neutrophils enter in membrane-bound… read more here.
Keywords: emperipolesis; emperipolesis mediates; intracytoplasmic neutrophils; megakaryocyte emperipolesis ... See more keywords