Safety and Efficacy of Empagliflozin and Diuretic Use in Patients with Heart Failure and Preserved Ejection Fraction: A Post Hoc Analysis of the EMPEROR-Preserved Trial.
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DOI: 10.1001/jamacardio.2023.1090
Abstract: Importance The diuretic effect of sodium-glucose cotransporter 2 inhibitors may result in interaction with background diuretic therapy in patients with heart failure and preserved ejection fraction (HFpEF). Objective To assess the safety and efficacy of… read more here.
Keywords: ejection fraction; heart failure; emperor preserved; use ... See more keywords
Cardiac and Kidney Benefits of Empagliflozin in Heart Failure Across the Spectrum of Kidney Function: Insights from the EMPEROR-Preserved Trial.
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DOI: 10.1002/ejhf.2857
Abstract: BACKGROUND In the EMPEROR-Preserved trial, empagliflozin improved clinical outcomes of patients with heart failure with preserved ejection fraction. In this pre-specified analysis, we aim to study the effect of empagliflozin on cardiovascular and kidney outcomes… read more here.
Keywords: emperor preserved; heart failure; without ckd; kidney ... See more keywords
Empagliflozin, irrespective of blood pressure, improves outcomes in heart failure with preserved ejection fraction: the EMPEROR-Preserved trial
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DOI: 10.1093/eurheartj/ehac693
Abstract: Abstract Aims Empagliflozin reduces the risk of cardiovascular death or heart failure (HF) hospitalization in patients with HF and preserved ejection fraction. This study aims to evaluate if systolic blood pressure (SBP) moderates these effects.… read more here.
Keywords: emperor preserved; 130 mmhg; failure; heart ... See more keywords
Effectiveness of empagliflozin in patients with heart failure and COPD: Results from EMPEROR-Preserved and EMPEROR-Reduced
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DOI: 10.1093/eurheartj/ehae666.1171
Abstract: Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are chronic, progressive syndromes that share numerous risk factors and clinical symptoms. We sought to analyse the relationship between COPD status and outcomes in patients receiving… read more here.
Keywords: heart; copd; copd status; emperor preserved ... See more keywords
Abstract 4136621: Efficacy of Empagliflozin in Heart Failure with Preserved Ejection Fraction is related to the presence of echocardiographic features of diastolic dysfunction in the EMPEROR-Preserved trial.
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DOI: 10.1161/circ.150.suppl_1.4136621
Abstract: Introduction: Efficacy of SGLT2i empagliflozin in Heart Failure is seen across the LVEF spectrum and in multiple clinical subgroups, with diverse mechanisms of action. We hypothesized that objective echo evidence of diastolic dysfunction (DD) in… read more here.
Keywords: diastolic dysfunction; empagliflozin heart; efficacy; emperor preserved ... See more keywords