rBmTI-6 attenuates pathophysiological and inflammatory parameters of induced emphysema in mice.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.01.066
Abstract: Protease/anti-protease imbalance is the main pathogenic mechanism of emphysema and protease inhibitors have been recognized as potential molecules to treat the disease conditions. In this work the rBmTI-6 first domain (rBmTI-6-D1), a recombinant Kunitz-type serine… read more here.
Keywords: rbmti; emphysema mice; induced emphysema; mice ... See more keywords
Effects of fine particulate PM2.5 on emphysema of mice via regulating FOXO3A/BIM axis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/20-50-a-54
Abstract: This study aims to investigate the role of PM2.5 exposure in inducing apoptosis of alveolar epithelial cells and thereafter emphysema in mice, and the underlying mechanism. PM2.5 exposure model in mice was constructed. Lung tissues… read more here.
Keywords: foxo3a bim; a549 cells; emphysema mice; bim ... See more keywords