Autophagy augmentation alleviates cigarette smoke‐induced CFTR‐dysfunction, ceramide‐accumulation and COPD‐emphysema pathogenesis
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DOI: 10.1016/j.freeradbiomed.2018.11.023
Abstract: ABSTRACT In this study, we aimed to investigate precise mechanism(s) of sphingolipid‐imbalance and resulting ceramide‐accumulation in COPD‐emphysema. Where, human and murine emphysema lung tissues or human bronchial epithelial cells (Beas2b) were used for experimental analysis.… read more here.
Keywords: accumulation; ceramide accumulation; copd emphysema; emphysema pathogenesis ... See more keywords