Identification and Empiric Evaluation of New Inhibitors of the Multidrug Transporter P-Glycoprotein (ABCB1)
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DOI: 10.3390/ijms24065298
Abstract: The expression of the drug efflux pump ABCB1 correlates negatively with cancer survival, making the transporter an attractive target for therapeutic inhibition. In order to identify new inhibitors of ABCB1, we have exploited the cryo-EM… read more here.
Keywords: inhibitors multidrug; identification empiric; evaluation new; identification ... See more keywords