Articles with "empirical treatment" as a keyword



Evaluation of empirical treatment for blood culture-negative endocarditis

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Published in 2017 at "Journal of Antimicrobial Chemotherapy"

DOI: 10.1093/jac/dkw362

Abstract: Objectives Much progress has been made in understanding the main causes of blood culture-negative endocarditis (BCNE). Few studies concerning BCNE treatment (due to previous antibiotics used or fastidious pathogens) are available. We performed this study… read more here.

Keywords: treatment; culture negative; empirical treatment; negative endocarditis ... See more keywords

1472. Antibiotic De-escalation Compared with Continued Empirical Treatment in Non-Ventilated Hospital-Acquired Pneumonia

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Published in 2018 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofy210.1302

Abstract: Abstract Background Antibiotic de-escalation is an important component of antimicrobial stewardship programs. Nosocomial pneumonia is the most common healthcare-associated infection with nonventilated hospital-acquired pneumonia (HAP) comprising the majority of cases. We aimed to compare antibiotic… read more here.

Keywords: treatment; hospital; continued empirical; empirical treatment ... See more keywords

Susceptibility pattern of bacterial isolates in equine ulcerative keratitis: Implications for empirical treatment at a university teaching hospital in Sydney.

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Published in 2022 at "Australian veterinary journal"

DOI: 10.1111/avj.13221

Abstract: Corneal ulceration is a common ophthalmic condition in horses. It is frequently caused by trauma to the corneal surface, followed by secondary infection by commensal or pathogenic organisms including Streptococcus equi subspecies zooepidemicus, Pseudomonas aeruginosa… read more here.

Keywords: empirical treatment; ulcerative keratitis; pseudomonas spp; susceptibility ... See more keywords

Empirical treatment of bacterial keratitis: an international survey of corneal specialists

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Published in 2017 at "BMJ Open Ophthalmology"

DOI: 10.1136/bmjophth-2016-000047

Abstract: Background/aims New antibiotic agents and changing susceptibility patterns may have changed the empirical treatment of bacterial keratitis. Our objective in this study was to survey cornea specialists’ practice patterns in the initial treatment of bacterial… read more here.

Keywords: treatment bacterial; bacterial keratitis; treatment; survey ... See more keywords

Statistical analysis plan for the “empirical treatment against cytomegalovirus and tuberculosis in HIV-infected infants with severe pneumonia” clinical trial

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Published in 2025 at "Trials"

DOI: 10.1186/s13063-025-08841-7

Abstract: The EMPIRICAL trial aims to assess safety and efficacy of an empirical treatment against cytomegalovirus (CMV) and tuberculosis (TB) compared to standard of care (SoC), on adverse events and 15-day and 1-year mortality among infants… read more here.

Keywords: treatment; clinical trial; empirical treatment; analysis ... See more keywords

Application of metagenomic next-generation sequencing in the diagnosis of infectious diseases of the central nervous system after empirical treatment

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Published in 2022 at "World Journal of Clinical Cases"

DOI: 10.12998/wjcc.v10.i22.7760

Abstract: BACKGROUND The diagnostic value of metagenomic next-generation sequencing (mNGS) in central nervous system (CNS) infectious diseases after empirical treatment has not been reported. AIM To investigate the diagnostic value of mNGS of cerebrospinal fluid (CSF)… read more here.

Keywords: empirical treatment; infectious diseases; diagnosis; infection ... See more keywords

Cefuroxime compared to piperacillin/tazobactam as empirical treatment of Escherichia coli bacteremia in a low Extended-spectrum beta-lactamase (ESBL) prevalence cohort

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Published in 2019 at "Infection and Drug Resistance"

DOI: 10.2147/idr.s197735

Abstract: Objectives: On January 18, 2010, a part of the capital region of Denmark shifted the empirical treatment of febrile conditions from cefuroxime to piperacillin/tazobactam. We compare empirical treatment with piperacillin/tazobactam versus cefuroxime for Escherichia coli… read more here.

Keywords: cefuroxime; treatment; empirical treatment; coli bacteremia ... See more keywords

Clinical Characteristics and Optimization of Empirical Antimicrobial Therapy for Febrile Neutropenia in Patients With Hematologic Malignancies

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Published in 2025 at "Infection and Drug Resistance"

DOI: 10.2147/idr.s493670

Abstract: Purpose Since the publication of the 2011 Infectious Diseases Society of America (IDSA) guidelines for empirical treatment of febrile neutropenia (FN), there have been significant shifts in pathogen profiles and emerging challenges in treatment. These… read more here.

Keywords: febrile neutropenia; empirical treatment; treatment; therapy ... See more keywords

Safety of megadose meropenem in the empirical treatment of nosocomial sepsis: a pilot randomized clinical trial.

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Published in 2023 at "Future microbiology"

DOI: 10.2217/fmb-2022-0170

Abstract: Objective: To evaluate the safety of megadose meropenem as empirical treatment of nosocomial sepsis. Materials & methods: Critically ill patients diagnosed with sepsis received either high-dose (2 g every 8 h) or megadose (4 g every 8 h) meropenem… read more here.

Keywords: sepsis; empirical treatment; treatment nosocomial; megadose meropenem ... See more keywords

Clinical effect of discordance in empirical treatment of cases with urinary tract infection accompanied by bacteremia.

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Published in 2017 at "Turkish journal of urology"

DOI: 10.5152/tud.2017.58538

Abstract: Objective It has been shown in previous studies that inadequate empirical treatment is associated with mortality in a variety of infections caused by Gram-negative bacteria. In this study, the clinical effect of discordance in empirical… read more here.

Keywords: discordance; treatment; effect; empirical treatment ... See more keywords