Articles with "empirically designed" as a keyword



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Genome-scale CRISPR screening at high sensitivity with an empirically designed sgRNA library

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Published in 2020 at "BMC Biology"

DOI: 10.1186/s12915-020-00905-1

Abstract: Background In recent years, large-scale genetic screens using the CRISPR/Cas9 system have emerged as scalable approaches able to interrogate gene function with unprecedented efficiency and specificity in various biological contexts. By this means, functional dependencies… read more here.

Keywords: genome scale; crispr; sgrna library; empirically designed ... See more keywords