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Large scale functional characterization of mutations and their susceptibility to targeted therapy

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Published in 2019 at "Annals of Oncology"

DOI: 10.1093/annonc/mdz413.120

Abstract: Abstract Background Extensive use of NGS profiling in precision oncology is uncovering a staggering amount of novel alterations in the sequenced genes. Strikingly, the number of variants of uncertain significance (VUS) increases linearly with the… read more here.

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