Advances in novel vaccines for foot and mouth disease: focus on recombinant empty capsids
Sign Up to like & getrecommendations! Published in 2019 at "Critical Reviews in Biotechnology"
DOI: 10.1080/07388551.2018.1554619
Abstract: Abstract Foot and mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, which causes severe economic losses in the livestock industry. Currently available vaccines are based on inactivated FMD virus (FMDV). Although inactivated… read more here.
Keywords: production; recombinant empty; foot mouth; mouth disease ... See more keywords
Analytical strategies for quantification of adeno-associated virus (AAV) empty capsids to support process development.
Sign Up to like & getrecommendations! Published in 2019 at "Human gene therapy methods"
DOI: 10.1089/hgtb.2019.088
Abstract: Recombinant adeno-associated virus (rAAV)-mediated gene therapy is a fast-evolving field in the biotechnology industry. One of the major challenges in developing a purification process for AAV gene therapy is establishing an effective yet scalable method… read more here.
Keywords: associated virus; process; adeno associated; process development ... See more keywords
Empty Adeno-Associated Virus Capsids: Contaminant or Natural Decoy?
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DOI: 10.1089/hum.2017.29039.trf
Abstract: AS MORE RECOMBINANT adeno-associated virus (rAAV) products are tested in or licensed for clinical use, the need for methods for large-scale, highquality manufacturing have increased proportionally. One of the recurring themes of recent advances in… read more here.
Keywords: product; purification; raav; adeno associated ... See more keywords
Development and Validation of an Anion-Exchange High-Performance Liquid Chromatography Method for Analysis of Empty Capsids and Capsids Encapsidating Genetic Material in a Purified Preparation of Recombinant Adeno-Associated Virus Serotype 5.
Sign Up to like & getrecommendations! Published in 2021 at "Human gene therapy"
DOI: 10.1089/hum.2020.317
Abstract: The development of various manufacturing platforms and analytical technologies has substantially contributed to successfully translating the recombinant adeno-associated viral vector from the lab to the clinic. The active deployment of these analytical technologies for process… read more here.
Keywords: genetic material; recombinant adeno; method; adeno associated ... See more keywords