EMT‐Induced Cell‐Mechanical Changes Enhance Mitotic Rounding Strength
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DOI: 10.1002/advs.202001276
Abstract: Abstract To undergo mitosis successfully, most animal cells need to acquire a round shape to provide space for the mitotic spindle. This mitotic rounding relies on mechanical deformation of surrounding tissue and is driven by… read more here.
Keywords: mechanical changes; emt; emt induced; mitotic rounding ... See more keywords
Aloe-Emodin Targeting FOXC2 Disrupts NETs Formation and EMT-Driven Postoperative Peritoneal Adhesion Through TGF-β1-Smad2/3 Pathway.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202511013
Abstract: Postoperative peritoneal adhesion (PPA) develops through TGF‐β1‐driven fibrotic remodeling, characterized by neutrophil extracellular trap (NETs)‐induced aberrant epithelial‐to‐mesenchymal transition (EMT) deposition. Although aloe‐emodin (AE) exhibits anti‐fibrosis potential, its molecular mechanisms remain elusive. Forkhead box protein C2… read more here.
Keywords: smad2 pathway; postoperative peritoneal; tgf smad2; emt ... See more keywords
Epithelial‐to‐mesenchymal transition as a learning paradigm of cell biology
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11967
Abstract: Epithelial‐to‐mesenchymal transition (EMT) is a complex biological process that occurs during normal embryogenesis and in certain pathological conditions, particularly in cancer. EMT can be viewed as a cell biology‐based process, since it involves all the… read more here.
Keywords: cell; mesenchymal transition; cell biology; epithelial mesenchymal ... See more keywords
Epithelial–mesenchymal transition and plasticity in the developmental basis of cancer and fibrosis
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24620
Abstract: Epithelial–mesenchymal transition (EMT) process epitomizes a change of cell phenotype that is typically reversible. Epithelial cells loosen cell–cell adhesion structures; including tight junctions, desmosomes, and adherens junctions, dismantle their polarity, and reorganize their cytoskeleton, switching… read more here.
Keywords: heart; fibrosis; emt; process ... See more keywords
Ectomesoderm and epithelial–mesenchymal transition‐related genes in spiralian development
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DOI: 10.1002/dvdy.24667
Abstract: Background: Spiralians (e.g., annelids, molluscs, and flatworms) possess two sources of mesoderm. One is from endodermal precursors (endomesoderm), which is considered to be the ancestral source in metazoans. The second is from ectoderm (ectomesoderm) and… read more here.
Keywords: mesenchymal transition; emt; ectomesoderm; epithelial mesenchymal ... See more keywords
miR-423-3p activates FAK signaling pathway to drive EMT process and tumor growth in lung adenocarcinoma through targeting CYBRD1.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24044
Abstract: BACKGROUND Lung adenocarcinoma (LUAD) is a malignant tumor with a high fatality rate and poor overall survival, while molecular targets diagnosing and alleviating lung cancer remain inadequate. METHODS In this article, we highlighted the upregulation… read more here.
Keywords: emt; cybrd1; mir; lung ... See more keywords
Phenomics Demonstrates Cytokines Additive Induction of Epithelial to Mesenchymal Transition
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.31491
Abstract: Epithelial to Mesenchymal Transition (EMT) is highly plastic with a program where cells lose adhesion and become more motile. EMT heterogeneity is one of the factors for disease progression and chemoresistance in cancer. Omics characterizations… read more here.
Keywords: mesenchymal transition; single cell; emt; cell ... See more keywords
Emodin inhibiting epithelial‐mesenchymal transition in pulmonary fibrosis through the c‐MYC/miR‐182‐5p/ZEB2 axis
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7680
Abstract: Emodin is a natural anthraquinone compound, which is the main component found in the traditional Chinese herb Polygonum cuspidatum. The anti‐fibrosis effects of Emodin have been reported. This study aimed to explore the specific mechanism… read more here.
Keywords: emt; myc mir; pulmonary fibrosis; fibrosis ... See more keywords
Methodologies for Following EMT In Vivo at Single Cell Resolution.
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DOI: 10.1007/978-1-0716-0779-4_23
Abstract: An epithelial-mesenchymal transition (EMT) occurs in almost every metazoan embryo at the time mesoderm begins to differentiate. Several embryos have a long record as models for studying an EMT given that a known population of… read more here.
Keywords: single cell; following emt; emt; methodologies following ... See more keywords
Generation of In Vitro Model of Epithelial Mesenchymal Transition (EMT) Via the Expression of a Cytoplasmic Mutant Form of Promylocytic Leukemia Protein (PML).
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7401-6_12
Abstract: Epithelial Mesenchymal Transition (EMT) is a key event in cancer progression. During this event, epithelial cancer cells undergo molecular and cellular changes leading to their trans-differentiation into mesenchymal cancer cells that are capable of migration,… read more here.
Keywords: mesenchymal transition; emt; transition emt; epithelial mesenchymal ... See more keywords
Ensifer-Mediated Transformation (EMT) of Rice (Monocot) and Oilseed Rape (Dicot).
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8778-8_3
Abstract: Ensifer adhaerens OV14 underpins the successful crop transformation protocol, termed Ensifer-mediated transformation (EMT). The adaptability and efficiency of EMT technology to successfully transform both monocot and dicots have been previously reported. To facilitate community users'… read more here.
Keywords: emt; rice; oilseed rape; transformation ... See more keywords