Inositol monophosphatase 1 (IMPA1) promotes triple‐negative breast cancer progression through regulating mTOR pathway and EMT process
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4970
Abstract: Triple‐negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, which is characterized by high heterogeneity and metabolic dysregulation. Inositol monophosphatase 1(IMPA1) is critical for the metabolism of inositol, which has profound effects… read more here.
Keywords: inositol; emt process; impa1; breast cancer ... See more keywords
TGF-β promote epithelial-mesenchymal transition via NF-κB/NOX4/ROS signal pathway in lung cancer cells.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06268-2
Abstract: Epithelial-mesenchymal transition (EMT), transforming growth factor β(TGF-β) and reactive oxygen species(ROS) plays a central role in cancer metastasis. Moreover, nicotinamide adenine dinucleotide phosphate 4(NOX4) is one of the main sources of ROS in lung cancer… read more here.
Keywords: lung cancer; nox4 ros; emt process; cancer cells ... See more keywords
Hsa_circ_0011946 promotes the migration and invasion of hepatocellular carcinoma by inducing EMT process.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202002_20161
Abstract: OBJECTIVE Recently, the vital role of circular RNAs is discovered in many diseases including tumor progression and metastasis. Hepatocellular carcinoma (HCC) is one of the most ordinary malignant tumors. The purpose of our study is… read more here.
Keywords: hsa circ; hcc; circ 0011946; emt process ... See more keywords
Exosomes Regulate the Epithelial–Mesenchymal Transition in Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.864980
Abstract: Exosomes are important mediators of intercellular communication and participate in complex biological processes by transferring a variety of bioactive molecules between cells. Epithelial–mesenchymal transition (EMT) is a process in which the cell phenotype changes from… read more here.
Keywords: emt process; mesenchymal transition; epithelial mesenchymal; tumor ... See more keywords
MicroRNA-214 promotes the EMT process in melanoma by downregulating CADM1 expression
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2020.11446
Abstract: Melanoma is a malignant skin cancer type associated with a high mortality rate, but its treatment is currently not ideal. Both microRNA (miR)-214 and cell adhesion molecule 1 (CADM1) are differentially expressed in melanoma, but… read more here.
Keywords: melanoma; expression; emt process; mir 214 ... See more keywords
Preliminary mechanisms of regulating PD‑L1 expression in non‑small cell lung cancer during the EMT process.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology reports"
DOI: 10.3892/or.2018.6474
Abstract: Non‑small cell lung cancer (NSCLC) is one of the most severe malignant tumor types worldwide. Recent studies have reported an important role of PD‑L1 in mediating immune evasion in the tumor microenvironment. In addition, increasing… read more here.
Keywords: cell; expression; emt process; non small ... See more keywords