Development and validation of a robust epithelial-mesenchymal transition (EMT)-related prognostic signature for hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2020.101587
Abstract: OBJECTIVE Epithelial-to-mesenchymal transition (EMT) is an essential biological process of cancer progression associated with increased metastatic potential and initiation. Herein, we aimed to develop and validate a robust EMT-related prognostic signature that could predict the… read more here.
Keywords: emt related; prognostic signature; hcc; analysis ... See more keywords
Comment on “Identification of EMT-related high-risk stage II colorectal cancer and characterisation of metastasis-related genes”
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Cancer"
DOI: 10.1038/s41416-020-01213-9
Abstract: We read with interest the publication by Wang et al., which describes the development, testing and validation of an epithelial-to-mesenchymal transition (EMT)-related transcriptional classifier to identify patients with stage II colorectal cancer (CRC) at risk… read more here.
Keywords: cancer; emt related; risk; cell ... See more keywords
An epithelial–mesenchymal transition-related long noncoding RNA signature correlates with the prognosis and progression in patients with bladder cancer
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20203944
Abstract: Abstract Bladder cancer is a common malignant tumour worldwide. Epithelial–mesenchymal transition (EMT)-related biomarkers can be used for early diagnosis and prognosis of cancer patients. To explore, accurate prediction models are essential to the diagnosis and… read more here.
Keywords: bladder cancer; patients bladder; cancer; signature ... See more keywords
Comprehensive analysis of partial epithelial mesenchymal transition‐related genes in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16099
Abstract: Increasing evidence has revealed that cancer cells undergoing an intermediate state, partial epithelial mesenchymal transition (p‐EMT), tend to metastasize rather than complete EMT. We performed a comprehensive analysis of E‐cadherin and 25 p‐EMT‐related genes in… read more here.
Keywords: emt related; mesenchymal transition; analysis; epithelial mesenchymal ... See more keywords
Identification and Validation of an Individualized EMT-Related Prognostic Risk Score Formula in Gastric Adenocarcinoma Patients
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DOI: 10.1155/2020/7082408
Abstract: Background The epithelial-mesenchymal transition (EMT) is a pivotal process for fibrotic disease, embryonic development, and wound healing. Moreover, some evidence has proven that the disorder of EMT also plays an important role in carcinogenesis, especially… read more here.
Keywords: emt related; gastric adenocarcinoma; risk score; value ... See more keywords
Development of a Prognostic Model Based on the Identification of EMT-Related lncRNAs in Triple-Negative Breast Cancer
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DOI: 10.1155/2021/9219961
Abstract: Background Triple-negative breast cancer (TNBC) remains the most incurable subtype of breast cancer owing to high heterogeneity, aggressive nature, and lack of treatment options. It is generally acknowledged that epithelial-mesenchymal transition (EMT) is the key… read more here.
Keywords: tnbc; breast cancer; model; emt related ... See more keywords
Establishment and Analysis of an Individualized EMT-Related Gene Signature for the Prognosis of Breast Cancer in Female Patients
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/1289445
Abstract: Background The current high mortality rate of female breast cancer (BC) patients emphasizes the necessity of identifying powerful and reliable prognostic signatures in BC patients. Epithelial-mesenchymal transition (EMT) was reported to be associated with the… read more here.
Keywords: female patients; breast cancer; analysis; model ... See more keywords
Identification of a Twelve Epithelial-Mesenchymal Transition-Related lncRNA Prognostic Signature in Kidney Clear Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/8131007
Abstract: Background Epithelial-mesenchymal transition (EMT) plays a vital role in tumor metastasis and drug resistance. It has been reported that EMT is regulated by several long noncoding RNAs (lncRNAs). We aimed to identify EMT-related lncRNAs and… read more here.
Keywords: lncrna prognostic; related lncrna; signature; prognostic signature ... See more keywords
Identification of EMT-Related lncRNAs as Potential Prognostic Biomarkers and Therapeutic Targets for Pancreatic Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/8259951
Abstract: Epithelial-mesenchymal transition (EMT) can promote carcinoma progression by multiple mechanisms; many studies demonstrated the invasiveness of pancreatic adenocarcinoma (PAAD) associated with the EMT, but how it acts through an lncRNA-dependent manner is unknown. Here, we… read more here.
Keywords: paad; risk; emt related; pancreatic adenocarcinoma ... See more keywords
Epithelial-to-Mesenchymal and Mesenchymal-to-Epithelial Transition in Mesenchymal Tumors: A Paradox in Sarcomas?
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DOI: 10.1158/0008-5472.can-17-0032
Abstract: The epithelial-to-mesenchymal transition (EMT) is a reversible process comprised of various subprograms via which epithelial cells reduce their intercellular adhesions and proliferative capacity while gaining a mesenchymal phenotype with increased migratory and invasive properties. This… read more here.
Keywords: emt related; transition; epithelial mesenchymal; mesenchymal mesenchymal ... See more keywords
Identification and validation of an epithelial-mesenchymal transition-related lncRNA pairs prognostic model for gastric cancer
Sign Up to like & getrecommendations! Published in 2023 at "Translational Cancer Research"
DOI: 10.21037/tcr-22-2751
Abstract: Background Gastric cancer (GC) is a common malignancy. A mounting body of evidence has demonstrated the correlation between GC prognosis and epithelial-mesenchymal transition (EMT)-related biomarkers. This research constructed an available model using EMT-related long noncoding… read more here.
Keywords: related lncrna; lncrna pairs; gastric cancer; model ... See more keywords