The role of Self Nano Emulsifying drug delivery systems of CDODA-Me in sensitizing Erlotinib resistant Nonsmall cell lung cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.01.010
Abstract: In this study we have investigated the effects of combination treatment involving ERL (Erlotinib) with a glycyrrhetinic acid analog, CDODA-Me in overcoming ERL resistance, and to improve the oral bioavailability of this treatment using self-Nano-emulsifying… read more here.
Keywords: combination; emulsifying drug; drug; self nano ... See more keywords
Investigation of Self-Emulsifying Drug-Delivery System Interaction with a Biomimetic Membrane under Conditions Relevant to the Small Intestine
Sign Up to like & getrecommendations! Published in 2021 at "Langmuir"
DOI: 10.1021/acs.langmuir.1c01689
Abstract: Self-emulsifying drug-delivery systems (SEDDS) have been extensively shown to increase oral absorption of solvation-limited compounds. However, there has been little clinical and commercial use of these formulations, in large part because the demonstrated advantages of… read more here.
Keywords: absorption; self emulsifying; drug delivery; emulsifying drug ... See more keywords
Preparation and characterisation of self-emulsifying drug delivery system (SEDDS) for enhancing oral bioavailability of metformin hydrochloride using hydrophobic ion pairing complexation
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2023.2170488
Abstract: Abstract Aim The aim of this study was preparation of a self-emulsifying drug delivery system (SEEDS) containing metformin hydrochloride. Methods Hydrophobic ion paired complexes were prepared by electrostatic interaction between metformin and sodium lauryl sulphate… read more here.
Keywords: self emulsifying; delivery system; emulsifying drug; drug delivery ... See more keywords
Self-emulsifying drug delivery system for enhanced solubility of asenapine maleate: design, characterization, in vitro, ex vivo and in vivo appraisal
Sign Up to like & getrecommendations! Published in 2019 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2019.1567758
Abstract: Abstract Self-emulsifying drug delivery systems (SES) were developed to improve oral bioavailability of asenapine maleate (ASM), an antipsychotic drug with challenging amphiphobic nature and extensive pre-systemic metabolism. ASM-SES was prepared by choosing the proportion of… read more here.
Keywords: self emulsifying; vitro vivo; vivo; emulsifying drug ... See more keywords
Self-emulsifying drug delivery systems: a novel approach to deliver drugs
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2083724
Abstract: Abstract Self-emulsifying drug delivery systems (SEDDS) are a proven method for poorly soluble substances works by increasing the solubility and bioavailability. SEDDS and isotropic mixtures, are composed of oils, surfactants, and occasionally cosolvents. The ability… read more here.
Keywords: self emulsifying; delivery systems; emulsifying drug; drug delivery ... See more keywords
Pharmacokinetics of a Single Intake of a Self-Emulsifying Drug Delivery System Containing the Triglyceride Form of DHA: A Randomized, Double-Blinded, Crossover Study
Sign Up to like & getrecommendations! Published in 2022 at "Current Developments in Nutrition"
DOI: 10.1093/cdn/nzac122
Abstract: ABSTRACT Background The health benefits of n–3 (ω-3) PUFAs are well studied. A self-emulsifying drug delivery system (SEDDS) is expected to improve n–3 PUFA absorption. Objectives The present study investigated how a single ingestion of… read more here.
Keywords: self emulsifying; dha; emulsifying drug; drug delivery ... See more keywords
A14823 In vitro characterization and pharmacodynamic evaluation of furosemide loaded self nano emulsifying drug delivery systems (SNEDDS)
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548312.49404.54
Abstract: Objectives: Poor water solubility is one of the reasons for erratic absorption after oral administration of furosemide (FSM), an antihypertensive loop diuretic. Self nano emulsifying drug delivery system (SNEDDS) is a novel drug delivery system… read more here.
Keywords: drug delivery; emulsifying drug; drug; self nano ... See more keywords
Improved Oral Pharmacokinetics of Pentoxifylline with Palm Oil and Capmul® MCM Containing Self-Nano-Emulsifying Drug Delivery System
Sign Up to like & getrecommendations! Published in 2020 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-020-01644-w
Abstract: Pentoxifylline (PTX), an anti-hemorrhage drug used in the treatment of intermittent claudication, is extensively metabolized by the liver resulting in a reduction of the therapeutic levels within a short duration of time. Self-nano-emulsifying drug delivery… read more here.
Keywords: drug delivery; emulsifying drug; drug; self nano ... See more keywords
Self-Emulsifying Drug Delivery System Enhances Tissue Distribution of Cinnamaldehyde by Altering the Properties of the Mucus Layer
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02416-4
Abstract: Oral delivery is considered the preferred route of administration due to its convenience and favorable compliance. However, this delivery often faces difficulties, such as poor solubility, limited absorption, and undesirable stability, especially for some volatile… read more here.
Keywords: self emulsifying; tissue distribution; emulsifying drug; drug delivery ... See more keywords
Development and in vitro Evaluation of Gastro-protective Aceclofenac-loaded Self-emulsifying Drug Delivery System
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s250242
Abstract: Aim Chronic use of oral nonsteroidal anti-inflammatory drugs (NSAIDs) is commonly associated with gastric irritation and gastric ulceration. Therefore, the aim of study was to develop a novel oral drug delivery system with minimum gastric… read more here.
Keywords: emulsifying drug; drug; self emulsifying; drug delivery ... See more keywords
Formulation, Characterization and Permeability Studies of Fenugreek (Trigonella foenum-graecum) Containing Self-Emulsifying Drug Delivery System (SEDDS)
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27092846
Abstract: Fenugreek is used as a spice and a traditional herbal medicine for a variety of purposes, given its antidiabetic and antioxidant effects. Self-emulsifying drug delivery systems (SEDDS) of herbal drugs are targets of extensive research… read more here.
Keywords: foenum graecum; self emulsifying; emulsifying drug; drug delivery ... See more keywords