Nanophotonics Enable Targeted Photothermal Silencing of Nociceptor Neurons.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202103364
Abstract: The sensory nervous and immune systems work in concert to preserve homeostasis. While this endogenous interplay protects from danger, it may drive chronic pathologies. Currently, genetic engineering of neurons remains the primary approach to interfere… read more here.
Keywords: nanophotonics enable; enable targeted; nociceptor; nociceptor neurons ... See more keywords
TF-PROTACs Enable Targeted Degradation of Transcription Factors.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c03852
Abstract: Transcription factors (TFs) represent a major class of therapeutic targets for the treatment of human diseases including cancer. Although the biological functions and even crystal structures of many TFs have been clearly elucidated, there is… read more here.
Keywords: degradation; protacs enable; targeted degradation; enable targeted ... See more keywords
A cellular platform to enable targeted brain delivery of T cells to glioblastoma.
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DOI: 10.1200/jco.2017.35.15_suppl.2053
Abstract: 2053Background: Poor T cell homing hinders the development of effective cell therapy for central nervous system (CNS) malignancies. Lessons learnt from inflammatory brain diseases can give insight into how to overcome the blood brain barrier… read more here.
Keywords: targeted brain; cellular platform; enable targeted; platform enable ... See more keywords