Conversion of racemic alcohols to optically pure amine precursors enabled by catalyst dynamic kinetic resolution: experiment and computation.
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DOI: 10.1039/d0cc02881a
Abstract: An unprecedented base metal catalysed asymmetric synthesis of α-chiral amine precursors from racemic alcohols is reported. This redox-neutral reaction utilises a bench-stable manganese complex and Ellman's sulfinamide as a versatile ammonia surrogate. DFT calculations explain… read more here.
Keywords: racemic alcohols; kinetic resolution; dynamic kinetic; enabled catalyst ... See more keywords