1,2-Oxygen Transposition on Arenes Enabled by Palladium/Norbornene Cooperative Catalysis.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.5c16468
Abstract: Phenols and their derivatives widely exist in bioactive molecules, and the position of phenolic oxygen can greatly influence their bioactivities. Thus, strategies that allow efficient relocation of oxygen substituents on arenes would be highly valuable… read more here.
Keywords: oxygen transposition; oxygen; transposition; palladium norbornene ... See more keywords
Thioether-enabled palladium-catalyzed atroposelective C–H olefination for N–C and C–C axial chirality
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DOI: 10.1039/d2sc00748g
Abstract: Thioethers allowed for highly atroposelective C–H olefinations by a palladium/chiral phosphoric acid catalytic system under ambient air. Both N–C and C–C axial chiral (hetero)biaryls were successfully constructed, leading to a broad range of axially chiral… read more here.
Keywords: palladium catalyzed; enabled palladium; atroposelective olefination; thioether enabled ... See more keywords
Direct Synthesis of Spirooxindoles Enabled by Palladium-Catalyzed Allylic Alkylation and DBU-Mediated Cyclization: Concept, Scope and Applications
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DOI: 10.1039/d4qo01275e
Abstract: Developing new methods for the rapid synthesis of complex spirooxindole skeletons from simple feedstocks is highly desirable in the context of medicinal chemistry and drug discovery. Herein we disclosed an... read more here.
Keywords: spirooxindoles enabled; chemistry; direct synthesis; synthesis spirooxindoles ... See more keywords