Rapid Determination of Enantiomeric Excess via NMR Spectroscopy: A Research-Informed Experiment
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DOI: 10.1021/acs.jchemed.6b00355
Abstract: An undergraduate chemistry experiment that draws from primary research is described. The experiment exploits chiral supramolecular assemblies for the determination of enantiomeric excess by 1H NMR spectroscopy. This report describes the delivery of the experiment… read more here.
Keywords: research; nmr spectroscopy; enantiomeric excess; determination enantiomeric ... See more keywords
A Real-Time Strategy for Chiroptical Sensing and Enantiomeric Excess Determination of Primary Amines via an Acid-Base Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02246
Abstract: Two achiral aromatic carboxylic acids that included the 1,8-naphthalimide group and an imidazolium cation were synthesized and exploited as chiroptical sensors. These compounds showed the real-time discrimination and enantiomeric excess determination of chiral amines and… read more here.
Keywords: excess determination; acid base; via acid; real time ... See more keywords
Data-Driven Prediction of Circular Dichroism-Based Calibration Curves for the Rapid Screening of Chiral Primary Amine Enantiomeric Excess Values.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c08127
Abstract: Here, we describe the prediction of the circular dichroism (CD) response of a three-component chiroptical sensor for enantiomeric excess (ee) determination of chiral amines using a multivariate fit to electronic and steric parameters. These computationally… read more here.
Keywords: calibration; prediction circular; calibration curves; enantiomeric excess ... See more keywords
Determination of enantiomeric excess with chirality-dependent ac Stark effects in cyclic three-level models
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DOI: 10.1103/physreva.100.033411
Abstract: Determination of enantiomeric excess is important and remains challenges. We theoretically propose a new spectroscopic method for this issue based on the chirality-dependent AC Stark effects in cyclic three-level models under the three-photon resonance condition.… read more here.
Keywords: dependent stark; enantiomeric excess; chirality dependent; determination enantiomeric ... See more keywords