Determination of enantiomeric impurity of tenofovir disoproxil fumarate on a cellulose tris(3,5-dichlorophenylcarbamate) chiral stationary phase and the characterization of its related substances.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202100011
Abstract: A simple and reliable HPLC method was developed to determine the enantiomeric impurity of tenofovir disoproxil fumarate, an orally bioavailable prodrug of tenofovir, commonly used for the treatment of human immunodeficiency virus and hepatitis B.… read more here.
Keywords: tenofovir disoproxil; enantiomeric impurity; disoproxil fumarate; tenofovir ... See more keywords
Development and Validation of the Chiral Liquid Chromatography Method for Separation of Enantiomeric Impurity in Novel Oxazolidinone Antibacterial Agent WCK 4086.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmy052
Abstract: A highly stereo-specific liquid chromatographic method was developed and validated for the quantification of enantiomeric impurity (R-enantiomer) in novel oxazolidinone antibacterial agent (WCK 4086), a drug substance. The separation was achieved on Chiralpak AD-H (amylose-based… read more here.
Keywords: enantiomeric impurity; wck 4086; method; novel oxazolidinone ... See more keywords