Sustainable and Continuous Synthesis of Enantiopure l‐Amino Acids by Using a Versatile Immobilised Multienzyme System
Sign Up to like & getrecommendations! Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201700493
Abstract: The enzymatic synthesis of α‐amino acids is a sustainable and efficient alternative to chemical processes, through which achieving enantiopure products is difficult. To more address this synthesis efficiently, a hierarchical architecture that irreversibly co‐immobilises an… read more here.
Keywords: system; amino acids; enantiopure; synthesis ... See more keywords
Biological Activities Evaluation of Enantiopure Isoxazolidine Derivatives: In Vitro, In Vivo and In Silico Studies
Sign Up to like & getrecommendations! Published in 2018 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-018-2868-2
Abstract: A series of enantiopure isoxazolidines (3a–c) were synthesized by 1,3-dipolar cycloaddition between a (−)-menthone-derived nitrone and various terminal alkenes. The screened compounds were evaluated for their antioxidant activity by two in vitro antioxidant assays, including… read more here.
Keywords: activities evaluation; biological activities; compared standard; evaluation enantiopure ... See more keywords
Cationic poly-amido-saccharides: stereochemically-defined, enantiopure polymers from anionic ring-opening polymerization of an amino-sugar monomer
Sign Up to like & getrecommendations! Published in 2020 at "Polymer Chemistry"
DOI: 10.1039/c9py01691k
Abstract: Efforts to develop synthetic carbohydrate polymers, despite their potential uses in biomedical applications, lag behind those of synthetic polypeptides and polynucleotides due to their structural complexity and the challenging methods associated with their synthesis. While… read more here.
Keywords: carbohydrate polymers; polymerization; poly amido; cationic poly ... See more keywords
From ferrocene to decasubstituted enantiopure ferrocene-1,1'-disulfoxide derivatives.
Sign Up to like & getrecommendations! Published in 2023 at "Dalton transactions"
DOI: 10.1039/d2dt03456e
Abstract: The functionalization of (R,R)-S,S'-di-tert-butylferrocene-1,1'-disulfoxide by deprotolithiation-electrophilic trapping sequences was studied towards polysubstituted, enantiopure derivatives for which the properties were determined. While the 2,2'-disubstituted ferrocene derivatives were obtained as expected, subsequent functionalization of the 2,2'-di(phenylthio) and… read more here.
Keywords: ferrocene decasubstituted; enantiopure; decasubstituted enantiopure; enantiopure ferrocene ... See more keywords
Production of enantiopure chiral aryl heteroaryl carbinols using whole‐cell Lactobacillus paracasei biotransformation
Sign Up to like & getrecommendations! Published in 2019 at "Synthetic Communications"
DOI: 10.1080/00397911.2019.1707226
Abstract: Abstract Aryl and heteroaryl chiral carbinols are useful precursors in the synthesis of drugs. Lactobacillus paracasei BD87E6, which is obtained from a cereal based fermented beverage, was investigated as whole cell biocatalyst for the bioreduction… read more here.
Keywords: production; lactobacillus paracasei; whole cell; enantiopure ... See more keywords
Crystal structures of racemic and enantiopure synephrine correlated with physicochemical properties from IR spectroscopy and thermal analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Acta crystallographica. Section C, Structural chemistry"
DOI: 10.1107/s2053229618014419
Abstract: The proto-alkaloid synephrine {SYN; systematic name: 4-[1-hydroxy-2-(methylamino)ethyl]phenol}, C9H13NO2, is found to crystallize as a neutral molecule in the racemate and as a zwitterion in the pure enantiomer, in which the phenolic H atom has been… read more here.
Keywords: analysis; synephrine; crystal structures; spectroscopy ... See more keywords
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27248808
Abstract: The design of enantiopure stereoisomers of N-2-phenylcyclopropylmethyl-substituted ortho-c oxide-bridged phenylmorphans, the E and Z isomers of an N-cinnamyl moiety, and N-propyl enantiomers were based on combining the most potent oxide-bridged phenylmorphan (the ortho-c isomer) with… read more here.
Keywords: enantiopure; bridged phenylmorphans; substituted ortho; oxide bridged ... See more keywords
Efficient Oxidative Resolution of 1-Phenylphosphol-2-Ene and Diels-Alder Synthesis of Enantiopure Bicyclic and Tricyclic P-Stereogenic C-P Heterocycles
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DOI: 10.3390/sym12030346
Abstract: 1-Phenylphosphol-2-ene 1-oxide is effectively resolved by L-menthyl bromoacetate to afford both SP and RP enantiomers of 1-phenylphosphol-2-ene 1-oxide on a multigram scale. The resolved 1-phenylphosphol-2-ene oxide has been found to undergo face-selective and endo-selective cycloadditions… read more here.
Keywords: ene oxide; stereogenic heterocycles; ene; phenylphosphol ene ... See more keywords