Enantioresolution and stereochemical characterization of two chiral sulfoxides endowed with COX-2 inhibitory activity.
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DOI: 10.1002/chir.22724
Abstract: The capacity of nonsteroidal antiinflammatory drugs (NSAIDs) to prevent prostanoids biosynthesis through the inhibition of COX-2 enzyme is related to their structural backbone, based on the fusion of a cis-stilbene unit with a variety of… read more here.
Keywords: chiral sulfoxides; two chiral; characterization two; enantioresolution stereochemical ... See more keywords