Enantioselective CE–MS analysis of ketamine metabolites in urine
Sign Up to like & getrecommendations! Published in 2022 at "Electrophoresis"
DOI: 10.1002/elps.202200175
Abstract: The chiral drug ketamine has long‐lasting antidepressant effects with a fast onset and is also suitable to treat patients with therapy‐resistant depression. The metabolite hydroxynorketamine (HNK) plays an important role in the antidepressant mechanism of… read more here.
Keywords: ketamine metabolites; ketamine; enantioselective analysis; chiral selector ... See more keywords
Enantioselective Analysis and Degradation Studies of Four Stereoisomers of Difenoconazole in Citrus by Chiral Liquid Chromatography-Tandem Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c05938
Abstract: Four difenoconazole stereoisomers were well separated on a Superchiral S-OX column. The absolute configurations of the four stereoisomers of difenoconazole eluted in an orderly fashion with the chiral column were confirmed as (2S,4S), (2S,4R), (2R,4R),… read more here.
Keywords: degradation studies; analysis degradation; four stereoisomers; enantioselective analysis ... See more keywords
Enantioselective Analysis of Mexiletine Using Chromatographic Techniques: A Review
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DOI: 10.2174/1573411016999201008125143
Abstract: Mexiletine belongs to the β-amino-aryl-ether group of pharmaceutical and applied in the diagnosis of antiarrhythmics, allodynia, and myotonic disorders. In its chemical structure, it possesses a chiral center and practiced in the form of the… read more here.
Keywords: analysis; enantioselective analysis; analysis mexiletine; chromatographic techniques ... See more keywords
Capillary Electrophoresis Mass Spectrometry: Developments and Applications for Enantioselective Analysis from 2011–2020
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27134126
Abstract: It is now more than 25 years since the first report of enantioselective analysis by capillary electrophoresis-mass spectrometry (CE-MS) appeared. This article reviews the power of chiral CE-MS in resolving issues on the use of… read more here.
Keywords: electrophoresis mass; enantioselective analysis; capillary electrophoresis; mass spectrometry ... See more keywords