Enantioselective Aza-Wacker-Type Cyclization Promoted by Pd-SPRIX Catalyst.
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DOI: 10.1021/acs.orglett.8b02946
Abstract: An enantioselective aza-Wacker-type reaction was developed. When alkenyl sulfonamide substrates were treated with the Pd-SPRIX catalyst in the presence of oxone as an oxidant, the olefin was attacked intramolecularly by the nitrogen nucleophile to construct… read more here.
Keywords: aza wacker; wacker type; enantioselective aza; sprix catalyst ... See more keywords
Impact of Host Flexibility on Selectivity in a Supramolecular Host-Catalyzed Enantioselective aza-Darzens Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c04182
Abstract: A highly enantioselective aza-Darzens reaction (up to 99% ee) catalyzed by an enantiopure supramolecular host has been discovered. To understand the role of host structure on reaction outcome, nine new gallium(III)-based enantiopure supramolecular assemblies were… read more here.
Keywords: enantioselective aza; supramolecular host; aza darzens; darzens reaction ... See more keywords