Organocatalytic Synthesis of α-Trifluoromethyl Allylboronic Acids by Enantioselective 1,2-Borotropic Migration
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DOI: 10.1021/jacs.0c09923
Abstract: Chiral α-substituted allylboronic acids were synthesized by asymmetric homologation of alkenylboronic acids using CF3/TMS-diazomethanes in the presence of BINOL catalyst and ethanol. The chiral α-substituted allylboronic acids were reacted with aldehydes or oxidized to alcohols… read more here.
Keywords: allylboronic acids; enantioselective borotropic; synthesis trifluoromethyl; trifluoromethyl allylboronic ... See more keywords