Enantioselective Au‐Catalyzed Synthesis of Thia[5]‐ and Thia[6]helicenes and Their Transformation into Bowl‐shaped Pleiadenes
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202211279
Abstract: A series of helically shaped benzo[b]chryseno[4,3‐d]thiophenes, naphtho[1,2‐b]phenanthro[4,3‐d]thiophenes, and chryseno[3,4‐b]naphtho[1,2‐d]thiophenes is synthesized via a highly enantioselective Au‐catalyzed intramolecular alkyne hydroarylation reaction. The inversion barriers of the structures obtained are determined both theoretically and experimentally, and their… read more here.
Keywords: enantioselective catalyzed; thia; catalyzed synthesis; transformation ... See more keywords
DFT Studies on the Mechanisms of Enantioselective Ni-Catalyzed Reductive Coupling Reactions to Form 1,1-diarylalkanes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2021.122042
Abstract: ABSTRACT The detail mechanisms of enantioselective Ni-catalyzed reductive coupling of 5-bromide-2-methoxypyridine (R1) and (1-chloropropyl) benzene (R2) to form 1,1-diarylalkanes (R, S)-P were studied using Density Functional Theory calculations. The overall catalytic cycles include the following… read more here.
Keywords: mechanisms enantioselective; form diarylalkanes; enantioselective catalyzed; reductive coupling ... See more keywords
Highly Diastereo- and Enantioselective Ir-Catalyzed Hydrogenation of 2,3-Disubstituted Quinolines with Structurally Fine-Tuned Phosphine-Phosphoramidite Ligands.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b03925
Abstract: A highly diastereo- and enantioselective Ir-catalyzed hydrogenation of unfunctionalized 2,3-disubstituted quinolines, especially 3-alkyl-2-arylquinolines, has been realized. The success of this hydrogenation is ascribed to the use of a structurally fine-tuned chiral phosphine-phosphoramidite ligand with a… read more here.
Keywords: highly diastereo; hydrogenation; catalyzed hydrogenation; diastereo enantioselective ... See more keywords
Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b13117
Abstract: A scalable enantioselective nickel-catalyzed electrochemical reductive homocoupling of aryl bromides has been developed, affording enantioenriched axially chiral biaryls in good yield under mild conditions using electricity as a reductant in an undivided cell. Common metal… read more here.
Keywords: synthesis biaryl; enantioselective catalyzed; catalyzed electrochemical; biaryl atropisomers ... See more keywords
Enantioselective Cu-catalyzed 1,4-additions of organozinc and Grignard reagents to enones: exceptional performance of the hydrido-phosphite-ligand BIFOP-H
Sign Up to like & getrecommendations! Published in 2019 at "New Journal of Chemistry"
DOI: 10.1039/c8nj05886e
Abstract: Enantioselective CuI-catalyzed 1,4-additions and DFT computations concerning the enantioselective mechanism. read more here.
Keywords: additions organozinc; organozinc grignard; enantioselective catalyzed; reagents enones ... See more keywords
Exploitation of Unconventional Electrophiles in Enantioselective Pd(0)-Catalyzed C-H Functionalizations.
Sign Up to like & getrecommendations! Published in 2019 at "Chimia"
DOI: 10.2533/chimia.2019.262
Abstract: Asymmetric metal-catalyzed C-H functionalization is a powerful strategy for the rapid generation of complex target molecules from simple precursors. While aryl (pseudo)halides have been used as electrophilic substrates in enantioselective Pd(0)-catalyzed syntheses of N-heterocycles, alternative… read more here.
Keywords: electrophiles enantioselective; unconventional electrophiles; catalyzed functionalizations; exploitation unconventional ... See more keywords