Catalytic Enantioselective Cyanation: Recent Advances and Perspectives
Sign Up to like & getrecommendations! Published in 2020 at "ACS Catalysis"
DOI: 10.1021/acscatal.0c01918
Abstract: α-Chiral nitriles are prevalent structural motifs in natural products, drugs, and pharmaceutically active compounds. In addition, because the cyano group can undergo various diversifying reactions,... read more here.
Keywords: catalytic enantioselective; cyanation recent; recent advances; advances perspectives ... See more keywords
Enantioselective cyanation of propargylic C-H bonds via cooperative photoredox and copper catalysis.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00410d
Abstract: Herein, we report an enantioselective cyanation of propargylic C-H bonds by combining photoredox catalysis with a copper-catalyzed radical relay in which the propargylic radical was generated by an intramolecular 1,5-HAT process. This reaction provides easy… read more here.
Keywords: catalysis; copper; cyanation propargylic; enantioselective cyanation ... See more keywords